P14

General Information (Source: NCBI Gene,UniProt)

Text mining Term P14
UniProt ID TCP4_MOUSE
Name Positive cofactor 4
PC4
Single-stranded DNA-binding protein p9
p14
Activated RNA polymerase II transcriptional coactivator p15
SUB1 homolog
Gene Names Sub1
Taxonomy Mus musculus

General annotation

Function General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
Subcellular location Nucleus.

Gene Ontology

GO:0006351 transcription, DNA-dependent BP

Sequence

>gi|6755364|ref|NP_035424.1| activated RNA polymerase II transcriptional coactivator p15 [Mus musculus]
MPKSKELVSSSSSGSDSDSEVEKKLKRKKQAVPEKPVKKQKPGETSRALASSKQSSSSRDDNMFQIGKMR
YVSVRDFKGKILIDIREYWMDSEGEMKPGRKGISLNMEQWSQLKEQISDIDDAVRKL

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSMUST00000110504
ENSMUST00000022816
UniGene Mm.41746
PDB
RefSeq NP_035424.1
Pfam PF02229