caspase 8

General Information (Source: NCBI Gene,UniProt)

Text mining Term caspase 8
UniProt ID Q3U607_MOUSE
Name Caspase 8, isoform CRA_a
Gene Names Casp8
Taxonomy Mus musculus

General annotation

Function
Subcellular location

Gene Ontology

GO:0030690 Noc1p-Noc2p complex CC
GO:0006915 apoptotic process BP
GO:0001525 angiogenesis BP
GO:0030225 macrophage differentiation BP
GO:0005739 mitochondrion CC
GO:0007507 heart development BP
GO:0001841 neural tube formation BP

Sequence

>gi|122056578|ref|NP_001073595.1| caspase-8 [Mus musculus]
MDFQSCLYAIAEELGSEDLAALKFLCLDYIPHKKQETIEDAQKLFLRLREKGMLEEGNLSFLKELLFHIS
RWDLLVNFLDCNREEMVRELRDPDNAQISPYRVMLFKLSEEVSELELRSFKFLLNNEIPKCKLEDDLSLL
EIFVEMEKRTMLAENNLETLKSICDQVNKSLLGKIEDYERSSTERRMSLEGREELPPSVLDEMSLKMAEL
CDSPREQDSESRTSDKVYQMKNKPRGYCLIINNHDFSKAREDITQLRKMKDRKGTDCDKEALSKTFKELH
FEIVSYDDCTANEIHEILEGYQSADHKNKDCFICCILSHGDKGVVYGTDGKEASIYDLTSYFTGSKCPSL
SGKPKIFFIQACQGSNFQKGVPDEAGFEQQNHTLEVDSSSHKNYIPDEADFLLGMATVKNCVSYRDPVNG
TWYIQSLCQSLRERCPQGDDILSILTGVNYDVSNKDDRRNKGKQMPQPTFTLRKKLFFPP

Options for BLAST

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Descriptions:

Database Cross Reference

Ensembl Gene
UniGene Mm.336851
PDB
RefSeq NP_001073595.1
NP_033942.1
Pfam PF00656
PF01335