caspase 8

General Information (Source: NCBI Gene,UniProt)

Text mining Term caspase 8
UniProt ID Q9JHX4_RAT
Name Uncharacterized protein
Caspase-8
Caspase 8, isoform CRA_a
Gene Names Casp8
Synonyms:CASP8
Taxonomy Rattus norvegicus

General annotation

Function
Subcellular location

Gene Ontology

GO:0005164 tumor necrosis factor receptor binding MF
GO:0045121 membrane raft CC
GO:0043005 neuron projection CC
GO:0006915 apoptotic process BP
GO:0032355 response to estradiol stimulus BP
GO:0045471 response to ethanol BP
GO:0005829 cytosol CC
GO:0046677 response to antibiotic BP
GO:0032025 response to cobalt ion BP
GO:0044297 cell body CC
GO:0031265 CD95 death-inducing signaling complex CC
GO:0051291 protein heterooligomerization BP
GO:0032496 response to lipopolysaccharide BP
GO:0009409 response to cold BP
GO:0004197 cysteine-type endopeptidase activity MF

Sequence

>gi|11560103|ref|NP_071613.1| caspase-8 [Rattus norvegicus]
MDFHSCLYDIAERLGNEELAALKFLCLDHIPQKKQESINDVLVLFQRLQEEGMLEEDNLSFLKELLFHIS
RRDLLSRVLKSSPEEMVRELQVLGKAQVSAYRVMLFKLSEDMDKEDLKSFKFLLITEIPKCKLQDNSSLL
DIFVEMEKRTILAENNLVTLKSICFRVNRSLLGRIDDYERSSTERRMSTEGGEELPVSVLDEVTIKMQDM
WDSPGEQESESLNSDNVYQMKSKPRGYCLIFNNNNFSKAREDIPKLSNMRDRKGTNYDEEALSKTFKELH
FEIVSFSDCTASQIHEVLVSYQSKDHKGKDCFICCILSHGDKGIVYGTDGKEASIYELTSYFTGSKCPSL
AGKPKIFFIQACQGNNFQKAVPVPDETGLEQEHVLEEDSSSYKNYIPDEADFLLGMATVKNCVSYRDPTR
GTWYIQSLCQSLRERCPRGEDILSILTGVNYDVSNKDNPRNMGKQMPQPIFTLRKKLFFPPN

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSRNOT00000016613
UniGene Rn.54474
PDB
RefSeq NP_071613.1
Pfam PF00656
PF01335