---

hexachlorobenzene

Identification (Source:EPA,EU)

ID	483
Name	hexachlorobenzene
CAS	118-74-1
IUPAC
Inchi	InChI=1S/C6Cl6/c7-1-2(8)4(10)6(12)5(11)3(1)9
CIPAC	161
EPA Code	061001
Formula	C6Cl6
SMILES	Clc1=c(Cl)c(Cl)=c(Cl)c(Cl)=c1Cl
Status	Not Approved

Classification

Mode of Action	Fumigant action on fungal spores
Pesticide Type	Fungicide, Metabolite
Chemical Group	Chlorinated aromatic hydrocarbon
Classification	aromatic fungicides

Properties (Source:PubChem)

Molecular Weight	284.80
Physical State	Colourless crystals
AlogP	5.816
H-Bond Donor	0
H-Bond Acceptor	0
Surface Area	222.21
Polar Surface Area	0.0

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	0.01 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	0.5 mg l-1
Birds	Acute		LD50	575 mg kg-1
Earthworms	Acute	14 day	LD50	1000 mg kg-1
Fish	Acute	96 hour	LC50	0.03 mg l-1
Mammals	Acute oral		LD50	> 10000 mg kg-1
	Bio-concentration factor		BCF	35000
	Bio-concentration factor		CT50	Not available days

Related targets

Target Name	RScore (About this table)
uroporphyrinogen decarboxylase	868(7,11,27,108)	Details
cytochrome P450 (protein family or complex)	1003(6,14,41,148)	Details
Ah receptor	253(2,3,5,53)	Details
demethylase	156(1,2,6,26)	Details
CYP1A2	119(1,1,4,24)	Details
coproporphyrinogen oxidase	102(1,1,4,7)	Details
estrogen receptor	100(1,1,2,15)	Details
IL 10	88(1,1,1,8)	Details
c Src	85(1,1,1,5)	Details
IL 5	83(1,1,1,3)	Details
progesterone receptor	82(1,1,1,2)	Details
androgen receptor	81(1,1,1,1)	Details
EGFR	74(0,2,3,9)	Details
glutamyl transpeptidase	76(0,1,6,21)	Details
ferrochelatase	59(0,1,4,14)	Details
thyroid stimulating hormone (protein family or complex)	56(0,1,3,16)	Details
glutathione S transferase	56(0,1,3,16)	Details
aryl hydrocarbon hydroxylase	44(0,1,2,9)	Details
Acetylcholinesterase	38(0,1,1,8)	Details
albumin	38(0,1,2,3)	Details
superoxide dismutase	37(0,1,1,7)	Details
catalase	35(0,1,1,5)	Details
glutathione reductase	34(0,1,1,4)	Details
Z protein	32(0,1,1,2)	Details
Men	32(0,1,1,2)	Details
thyroxine binding globulin	32(0,1,1,2)	Details
protein is	32(0,1,1,2)	Details
G beta	31(0,1,1,1)	Details
CBs 1	31(0,1,1,1)	Details
immunoglobulin (protein family or complex)	28(0,0,3,13)	Details
muscles	26(0,0,2,16)	Details
pg m	24(0,0,2,14)	Details
POLL	23(0,0,1,18)	Details
SPMD	23(0,0,2,13)	Details
CYP2B	21(0,0,3,6)	Details
ferritin (protein family or complex)	21(0,0,2,11)	Details
CYP1A1	20(0,0,1,15)	Details
Glutathione S transferase pi	20(0,0,2,10)	Details
thyroid peroxidase	20(0,0,2,10)	Details
cytochrome c	17(0,0,2,7)	Details
IgE	17(0,0,1,12)	Details
protein tyrosine kinase	16(0,0,2,6)	Details
cytokine receptor (protein family or complex)	15(0,0,2,5)	Details
APPI	14(0,0,2,4)	Details
IL 4	13(0,0,0,13)	Details
PEPCK	12(0,0,1,7)	Details
c fos	11(0,0,1,6)	Details
c jun	10(0,0,1,5)	Details
G6PD	10(0,0,1,5)	Details
carcinoembryonic antigen	10(0,0,1,5)	Details
cholinesterase	9(0,0,1,4)	Details
c Myc	9(0,0,1,4)	Details
integrin linked kinase	9(0,0,1,4)	Details
glucose 6 phosphate dehydrogenase	9(0,0,1,4)	Details
beta N acetylglucosaminidase	9(0,0,1,4)	Details
parathyroid hormone	9(0,0,1,4)	Details
cytochrome P450 3A4	9(0,0,1,4)	Details
delta aminolevulinate dehydratase	8(0,0,1,3)	Details
K ras	8(0,0,1,3)	Details
ornithine decarboxylase	8(0,0,1,3)	Details
PPARalpha	8(0,0,1,3)	Details
Anas	8(0,0,1,3)	Details
serine palmitoyltransferase (protein family or complex)	7(0,0,1,2)	Details
IL 2 receptor	7(0,0,1,2)	Details
cytochrome b5	7(0,0,1,2)	Details
interferon gamma	7(0,0,1,2)	Details
CD4	7(0,0,1,2)	Details
phosphoenolpyruvate carboxykinase	7(0,0,1,2)	Details
transferase	7(0,0,0,7)	Details
CD8	7(0,0,1,2)	Details

Docunmentation of Network Visuallization