eukaryotic translation initiation factor 4E

General Information (Source: NCBI Gene,UniProt)

Text mining Term eukaryotic translation initiation factor 4E
UniProt ID IF4E1_WHEAT
Name eIF4E-1
eIF-4F p26 subunit
eIF-4F 25 kDa subunit
mRNA cap-binding protein
eIF-4E-1
Eukaryotic translation initiation factor 4E-1
Gene Names
Taxonomy Triticum aestivum

General annotation

Function Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
Subcellular location

Gene Ontology

GO:0006417 regulation of translation BP
GO:0005737 cytoplasm CC
GO:0003743 translation initiation factor activity MF

Sequence

>gi|149242166|pdb|2IDV|A Chain A, Crystal Structure Of Wheat C113s Mutant Eif4e Bound To 7- Methyl-Gdp
AHPLENAWTFWFDNPQGKSRQVAWGSTIHPIHTFSTVEDFWGLYNNIHNPSKLNVGADFHCFKNKIEPKW
EDPISANGGKWTISCGRGKSDTFWLHTLLAMIGEQFDFGDEICGAVVSVRQKQERVAIWTKNAANEAAQI
SIGKQWKEFLDYKDSIGFIVHEDAKRSDKGPKNRYTV

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Database Cross Reference

Ensembl Gene
UniGene Ta.48486
PDB 2IDV
2IDR
RefSeq
Pfam PF01652