profilin (protein family or complex)

General Information (Source: NCBI Gene,UniProt)

Text mining Term profilin (protein family or complex)
UniProt ID PROF_HELAN
Name Profilin
Pollen allergen Hel a 2
Gene Names
Taxonomy Helianthus annuus

General annotation

Function Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
Subcellular location Cytoplasm, cytoskeleton (By similarity).

Gene Ontology

GO:0005737 cytoplasm CC
GO:0030036 actin cytoskeleton organization BP
GO:0015629 actin cytoskeleton CC
GO:0003779 actin binding MF

Sequence

>gi|3581965|emb|CAA75506.1| profilin [Helianthus annuus]
MSWQAYVDEHLMCDIEGTGQHLTSAAILGLDGTVWAQSAKFPQFKPEEMKGIIKEFDEAGTLAPTGMFIA
GAKYMVLQGEPGAVIRGKKGAGGICIKKTGQAMIMGIYDEPVAPGQCNMVVERLGDYLLEQGM

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq
Pfam PF00235