glutathione reductase

General Information (Source: NCBI Gene,UniProt)

Text mining Term glutathione reductase
UniProt ID GSHRC_PEA
Name GR
Glutathione reductase, cytosolic
GRase
GOR2
Gene Names
Taxonomy Pisum sativum

General annotation

Function Maintains high levels of reduced glutathione in the cytosol. May play a role in the restoration of the post-stress redox state of the cytosolic glutathione pool.
Subcellular location Cytoplasm.

Gene Ontology

GO:0004362 glutathione-disulfide reductase activity MF
GO:0050661 NADP binding MF
GO:0050660 flavin adenine dinucleotide binding MF
GO:0005737 cytoplasm CC
GO:0006749 glutathione metabolic process BP
GO:0045454 cell redox homeostasis BP

Sequence

>gi|1370285|emb|CAA66924.1| glutathione reductase [Pisum sativum]
MARKMLNDGEPDLKKGEEQGKVYDFDLFIIGAGSGGVRAARFSSNFGAKVGICELPFHPISSETIGGVGG
TCVIRGCVPKKILVYGASYGGELQDARNFGWELNENVDFNWKKLLQKKTDEINRLNGIYKRLLSNAGVKL
FEGEGKIASPNEVEVTQLDGTKLSYSAKHILIATGSRAQRPNIPGQELGITSDEALSLEEFPKRAVILGG
GYIAVEFASIWRGMGSSVNLVFRKELPLRGFDDEMRAVVARNLEGRGINLHPRTNLAQLIKTEDGIKVIT
DHGEELIADVVLFATGRSPNSKRLNLEKVGVEFDKAGAIVVDEYSRTNIPSIWAVGDVTNRLNLTPVALM
EASLFAKTVFGGQASKPDYNDIPYAVFCIPPLSVVGLSEEQAVEQTKGDVLIFTSTFNPMKNTISGRQEK
TVMKLVVDAQTDKVLGASMCGPDAPEIVQGIAIAIKCGATKAQFDSTVGIHPSSAEEFVTMRSETRRVTG
GVKPKTNL

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq
Pfam PF02852
PF07992
PF00070