glutathione reductase

General Information (Source: NCBI Gene,UniProt)

Text mining Term glutathione reductase
UniProt ID GSHR_NEUCR
Name GRase
GR
Glutathione reductase
Gene Names
Taxonomy Neurospora crassa OR74A

General annotation

Function Maintains high levels of reduced glutathione in the cytosol (By similarity).
Subcellular location Cytoplasm (By similarity).

Gene Ontology

GO:0050661 NADP binding MF
GO:0050660 flavin adenine dinucleotide binding MF
GO:0004362 glutathione-disulfide reductase activity MF
GO:0006749 glutathione metabolic process BP
GO:0045454 cell redox homeostasis BP
GO:0005737 cytoplasm CC

Sequence

>gi|85079936|ref|XP_956448.1| glutathione reductase [Neurospora crassa OR74A]
MAPISRETDFLVIGGGSGGIATARAAAGKYGIKSMVVEGKRLGGTCVNVGCVPKKVTFYAALVAETIHQA
KDYGFSVEQTAPFDWPTFKQKRDAYVARLNGIYERNLANDKVEYVHGWAKLLSPNSVEVTLDDGTKSVVN
AKKILIAVGGNPTIPPHIPGSEYGTNSDGFFDIDTLPKKVALVGAGYIAVEFAGMLNALGVETHLFIRHD
TFLRSFDPMIQQVSVKEYERIGVKVHKKSQLTSVQKDAAGKLAINFKEGEGEQSISDVDHLIWAVGRTPA
VEGLGLDKAGVKTNEKGYIEVDEYQNTSTENIYAVGDVCGQVELTPVAIAAGRKLAARLFGPEEFRTLKL
NYDNVPSVVFAHPEIGSIGLTEPEAVAKYGAENLKIYKSSFTAMYYAMMKPEDKAPTAYKLICAGPEEKV
VGLHIIGLGSGEILQGFGVAVNMGATKADFDNCVAIHPTSAEELVTLK

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq XP_956448.1
Pfam PF07992
PF00070
PF02852