nociceptin receptor

General Information (Source: NCBI Gene,UniProt)

Text mining Term nociceptin receptor
UniProt ID OPRX_RAT
Name KOR-3
XOR1
Kappa-type 3 opioid receptor
Nociceptin receptor
Orphanin FQ receptor
ROR-C
Gene Names Oprl1
Taxonomy Rattus norvegicus

General annotation

Function Receptor for the neuropeptide nociceptin/orphanin FQ. Has a potential role in modulating a number of brain functions, including instinctive behaviors and emotions. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase.
Subcellular location Cell membrane; Multi-pass membrane protein.

Gene Ontology

GO:0005886 plasma membrane CC
GO:0016021 integral to membrane CC

Sequence

>gi|13928772|ref|NP_113757.1| nociceptin receptor [Rattus norvegicus]
MESLFPAPYWEVLYGSHFQGNLSLLNETVPHHLLLNASHSAFLPLGLKVTIVGLYLAVCIGGLLGNCLVM
YVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTA
MSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPAPQDYWGP
VFAICIFLFSFIIPVLIISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFV
LVQGLGVQPGSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASSLHREMQVSDRVRSIA
KDVGLGCKTSETVPRPA

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSRNOT00000045845
UniGene Rn.9762
PDB
RefSeq NP_113757.1
Pfam PF00001