annexin V

General Information (Source: NCBI Gene,UniProt)

Text mining Term annexin V
UniProt ID ANXA5_RAT
Name Annexin V
Annexin-5
Placental anticoagulant protein I
Anchorin CII
Vascular anticoagulant-alpha
PAP-I
Placental anticoagulant protein 4
Thromboplastin inhibitor
CBP-I
Calphobindin I
VAC-alpha
Lipocortin V
Annexin A5
Endonexin II
PP4
Gene Names Anxa5
Synonyms:Anx5
Taxonomy Rattus norvegicus

General annotation

Function This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
Subcellular location

Gene Ontology

GO:0005544 calcium-dependent phospholipid binding MF
GO:0051260 protein homooligomerization BP
GO:0030971 receptor tyrosine kinase binding MF
GO:0042383 sarcolemma CC
GO:0005737 cytoplasm CC
GO:0007596 blood coagulation BP
GO:0014704 intercalated disc CC
GO:0043065 positive regulation of apoptotic process BP
GO:0042995 cell projection CC
GO:0050819 negative regulation of coagulation BP
GO:0005509 calcium ion binding MF

Sequence

>gi|6978505|ref|NP_037264.1| annexin A5 [Rattus norvegicus]
MALRGTVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSE
LTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVV
GDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDK
YMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLF
NIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD

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Database Cross Reference

Ensembl Gene
UniGene Rn.3318
PDB 1BCZ
2H0L
1G5N
1A8A
2RAN
1N42
1A8B
2H0K
1N44
2IE6
2H0M
1BC1
1BC3
2IE7
1N41
1BCW
1BCY
1BC0
RefSeq NP_037264.1
Pfam PF00191