Substance P

General Information (Source: NCBI Gene,UniProt)

Text mining Term Substance P
UniProt ID TKN1_MOUSE
Name Neuromedin L
Neuropeptide K
Substance P
NPK
NKA
Neurokinin A
Neuropeptide gamma
Substance K
PPT
C-terminal-flanking peptide
Protachykinin-1
Gene Names Tac1
Taxonomy Mus musculus

General annotation

Function Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
Subcellular location Secreted.

Gene Ontology

GO:0007217 tachykinin receptor signaling pathway BP
GO:0006954 inflammatory response BP
GO:0043025 neuronal cell body CC
GO:0007218 neuropeptide signaling pathway BP
GO:0048265 response to pain BP
GO:0019233 sensory perception of pain BP
GO:0007268 synaptic transmission BP
GO:0030424 axon CC

Sequence

>gi|6678207|ref|NP_033337.1| protachykinin-1 precursor [Mus musculus]
MKILVAVAVFFLVSTQLFAEEIDANDDLNYWSDWSDSDQIKEAMPEPFEHLLQRIARRPKPQQFFGLMGK
RDADSSVEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERSAMQNYERRRK

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSMUST00000090679
ENSMUST00000115546
UniGene Mm.1440
Mm.410823
PDB
RefSeq NP_033337.1
Pfam