| Text mining Term | progesterone receptor |
|---|---|
| UniProt ID | PRGR_RAT |
| Name |
Nuclear receptor subfamily 3 group C member 3 PR Progesterone receptor |
| Gene Names |
Pgr
Synonyms:Nr3c3 |
| Taxonomy | Rattus norvegicus |
| Function |
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform is involved in activation of c-SRC/MAPK signaling on hormone stimulation (By similarity). |
|---|---|
| Subcellular location |
Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both homone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases (By similarity). |
| GO:0045893 | positive regulation of transcription, DNA-dependent | BP |
| GO:0001553 | luteinization | BP |
| GO:0005496 | steroid binding | MF |
| GO:0071372 | cellular response to follicle-stimulating hormone stimulus | BP |
| GO:0045892 | negative regulation of transcription, DNA-dependent | BP |
| GO:0016101 | diterpenoid metabolic process | BP |
| GO:0042562 | hormone binding | MF |
| GO:0008270 | zinc ion binding | MF |
| GO:0006351 | transcription, DNA-dependent | BP |
| GO:0003700 | sequence-specific DNA binding transcription factor activity | MF |
| GO:0005634 | nucleus | CC |
| GO:0043565 | sequence-specific DNA binding | MF |
| GO:0003707 | steroid hormone receptor activity | MF |
| GO:0071373 | cellular response to luteinizing hormone stimulus | BP |
| GO:0005829 | cytosol | CC |
| GO:0043005 | neuron projection | CC |
>gi|12408292|ref|NP_074038.1| progesterone receptor [Rattus norvegicus] MTELQAKDPRTLHTSGAAPSPTHVGSPLLARLDPDPFQGSQHSDASSVVSPIPISLDRLLFSRSCQAQEL PDEKTQNQQSLSDVEGAFSGVEASRRRSRNPRAPEKDSRLLDSVLDTLLAPSGPEQSQTSPPACEAITSW CLFGPELPEDPRSVPATKGLLSPLMSRPESKAGDSSGTGAGQKVLPKAVSPPRQLLLPTSGSAHWPGAGV KPSQQPATVEVEEDGGLETEGSAGPLLKSKPRALEGMCSGGGVTANAPGAAPGGVTLVPKEDSRFSAPRV SLEQDAPVAPGRSPLATTVVDFIHVPILPLNHALLAARTRQLLEGDSYDGGAAAQVPFAPPRGSPSAPSP PVPCGDFPDCTYPPEGDPKEDGFPVYGEFQPPGLKIKEEEEGTEAASRSPRPYLLAGASAATFPDFPLPP RPPRAPPSRPGEAAVAAPSAAVSPVSSSGSALECILYKAEGAPPTQGSFAPLPCKPPAASSCLLPRDSLP AAPTSSAAPAIYPPLGLNGLPQLGYQAAVLKDSLPQVYPPYLNYLRPDSEASQSPQYGFDSLPQKICLIC GDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFK KFNKVRVMRALDGVALPQSVAFPNESQTLGQRITFSPNQEIQLVPPLINLLMSIEPDVVYAGHDNTKPDT SSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAP DLILNEQRMKELSFYSLCLTMWQIPQEFVKLQVTHEEFLCMKVLLLLNTIPLEGLRSQSQFEEMRSSYIR ELIKAIGLRQKGVVPSSQRFYQLTKLLDSLHDLVKQLHLYCLNTFIQSRALAVEFPEMMSEVIAAQLPKI LAGMVKPLLFHKK |
| Ensembl Gene | |
|---|---|
| UniGene |
Rn.10303 |
| PDB | |
| RefSeq |
NP_074038.1 |
| Pfam |
PF00105 PF00104 PF02161 |