catalase

General Information (Source: NCBI Gene,UniProt)

Text mining Term catalase
UniProt ID CATA_MOUSE
Name Catalase
Gene Names Cat
Taxonomy Mus musculus

General annotation

Function Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells.
Subcellular location Peroxisome.

Gene Ontology

GO:0009060 aerobic respiration BP
GO:0042744 hydrogen peroxide catabolic process BP
GO:0032088 negative regulation of NF-kappaB transcription factor activity BP
GO:0020027 hemoglobin metabolic process BP
GO:0006641 triglyceride metabolic process BP
GO:0051092 positive regulation of NF-kappaB transcription factor activity BP
GO:0005778 peroxisomal membrane CC
GO:0051781 positive regulation of cell division BP
GO:0004096 catalase activity MF
GO:0008203 cholesterol metabolic process BP
GO:0004046 aminoacylase activity MF
GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade BP

Sequence

>gi|157951741|ref|NP_033934.2| catalase [Mus musculus]
MSDSRDPASDQMKQWKEQRASQRPDVLTTGGGNPIGDKLNIMTAGSRGPLLVQDVVFTDEMAHFDRERIP
ERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVTGESGSADTVRDPRGFAVKFYTED
GNWDLVGNNTPIFFIRDAILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHR
HMNGYGSHTFKLVNADGEAVYCKFHYKTDQGIKNLPVGEAGRLAQEDPDYGLRDLFNAIANGNYPSWTFY
IQVMTFKEAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNKNPVNYFAEVEQMAFDPSNMPPGIEPSPDKM
LQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMHDNQGGAPNYYPNSFSAPEQQRSALE
HSVQCAVDVKRFNSANEDNVTQVRTFYTKVLNEEERKRLCENIAGHLKDAQLFIQKKAVKNFTDVHPDYG
ARIQALLDKYNAEKPKNAIHTYTQAGSHMAAKGKANL

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSMUST00000028610
UniGene Mm.4215
PDB
RefSeq NP_033934.2
Pfam PF06628
PF00199