Text mining Term | brain derived neurotrophic factor |
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UniProt ID | BDNF_MOUSE |
Name |
BDNF Brain-derived neurotrophic factor |
Gene Names |
Bdnf
|
Taxonomy | Mus musculus |
Function |
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. |
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Subcellular location |
Secreted. |
GO:0005788 | endoplasmic reticulum lumen | CC |
GO:0019222 | regulation of metabolic process | BP |
GO:0008083 | growth factor activity | MF |
GO:0007631 | feeding behavior | BP |
GO:0016023 | cytoplasmic membrane-bounded vesicle | CC |
GO:0007411 | axon guidance | BP |
GO:0048839 | inner ear development | BP |
GO:0016358 | dendrite development | BP |
GO:0005576 | extracellular region | CC |
GO:0042596 | fear response | BP |
GO:0014047 | glutamate secretion | BP |
GO:0001657 | ureteric bud development | BP |
GO:0043524 | negative regulation of neuron apoptosis | BP |
GO:0007611 | learning or memory | BP |
GO:0046668 | regulation of retinal cell programmed cell death | BP |
GO:0045666 | positive regulation of neuron differentiation | BP |
GO:0021675 | nerve development | BP |
GO:0007406 | negative regulation of neuroblast proliferation | BP |
GO:0007412 | axon target recognition | BP |
GO:0008038 | neuron recognition | BP |
GO:0048167 | regulation of synaptic plasticity | BP |
GO:0042493 | response to drug | BP |
GO:0006916 | anti-apoptosis | BP |
>gi|114326459|ref|NP_001041607.1| brain-derived neurotrophic factor isoform 2 precursor [Mus musculus] MTILFLTMVISYFGCMKAAPMKEVNVHGQGNLAYPGVRTHGTLESVNGPRAGSRGLTTTSLADTFEHVIE ELLDEDQKVRPNEENHKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGEL SVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQC RTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR |