Text mining Term | brain derived neurotrophic factor |
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UniProt ID | BDNF_MOUSE |
Name |
Brain-derived neurotrophic factor BDNF |
Gene Names |
Bdnf
|
Taxonomy | Mus musculus |
Function |
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. |
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Subcellular location |
Secreted. |
GO:0043524 | negative regulation of neuron apoptosis | BP |
GO:0005788 | endoplasmic reticulum lumen | CC |
GO:0048167 | regulation of synaptic plasticity | BP |
GO:0008038 | neuron recognition | BP |
GO:0048839 | inner ear development | BP |
GO:0019222 | regulation of metabolic process | BP |
GO:0021675 | nerve development | BP |
GO:0046668 | regulation of retinal cell programmed cell death | BP |
GO:0008083 | growth factor activity | MF |
GO:0042596 | fear response | BP |
GO:0016358 | dendrite development | BP |
GO:0001657 | ureteric bud development | BP |
GO:0016023 | cytoplasmic membrane-bounded vesicle | CC |
GO:0007406 | negative regulation of neuroblast proliferation | BP |
GO:0007611 | learning or memory | BP |
GO:0007412 | axon target recognition | BP |
GO:0014047 | glutamate secretion | BP |
GO:0007411 | axon guidance | BP |
GO:0007631 | feeding behavior | BP |
GO:0006916 | anti-apoptosis | BP |
GO:0042493 | response to drug | BP |
GO:0045666 | positive regulation of neuron differentiation | BP |
GO:0005576 | extracellular region | CC |
>gi|114326457|ref|NP_001041604.1| brain-derived neurotrophic factor isoform 2 precursor [Mus musculus] MTILFLTMVISYFGCMKAAPMKEVNVHGQGNLAYPGVRTHGTLESVNGPRAGSRGLTTTSLADTFEHVIE ELLDEDQKVRPNEENHKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGEL SVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQC RTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR |