Text mining Term | brain derived neurotrophic factor |
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UniProt ID | BDNF_MOUSE |
Name |
Brain-derived neurotrophic factor BDNF |
Gene Names |
Bdnf
|
Taxonomy | Mus musculus |
Function |
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. |
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Subcellular location |
Secreted. |
GO:0014047 | glutamate secretion | BP |
GO:0042596 | fear response | BP |
GO:0048167 | regulation of synaptic plasticity | BP |
GO:0019222 | regulation of metabolic process | BP |
GO:0007406 | negative regulation of neuroblast proliferation | BP |
GO:0007412 | axon target recognition | BP |
GO:0043524 | negative regulation of neuron apoptosis | BP |
GO:0007631 | feeding behavior | BP |
GO:0042493 | response to drug | BP |
GO:0008038 | neuron recognition | BP |
GO:0007611 | learning or memory | BP |
GO:0007411 | axon guidance | BP |
GO:0048839 | inner ear development | BP |
GO:0005576 | extracellular region | CC |
GO:0008083 | growth factor activity | MF |
GO:0016358 | dendrite development | BP |
GO:0021675 | nerve development | BP |
GO:0006916 | anti-apoptosis | BP |
GO:0045666 | positive regulation of neuron differentiation | BP |
GO:0016023 | cytoplasmic membrane-bounded vesicle | CC |
GO:0005788 | endoplasmic reticulum lumen | CC |
GO:0001657 | ureteric bud development | BP |
GO:0046668 | regulation of retinal cell programmed cell death | BP |
>gi|114326461|ref|NP_001041606.1| brain-derived neurotrophic factor isoform 2 precursor [Mus musculus] MTILFLTMVISYFGCMKAAPMKEVNVHGQGNLAYPGVRTHGTLESVNGPRAGSRGLTTTSLADTFEHVIE ELLDEDQKVRPNEENHKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGEL SVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQC RTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR |