Text mining Term | brain derived neurotrophic factor |
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UniProt ID | BDNF_MOUSE |
Name |
BDNF Brain-derived neurotrophic factor |
Gene Names |
Bdnf
|
Taxonomy | Mus musculus |
Function |
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. |
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Subcellular location |
Secreted. |
GO:0019222 | regulation of metabolic process | BP |
GO:0005788 | endoplasmic reticulum lumen | CC |
GO:0007631 | feeding behavior | BP |
GO:0007611 | learning or memory | BP |
GO:0046668 | regulation of retinal cell programmed cell death | BP |
GO:0007406 | negative regulation of neuroblast proliferation | BP |
GO:0008038 | neuron recognition | BP |
GO:0042596 | fear response | BP |
GO:0007412 | axon target recognition | BP |
GO:0005576 | extracellular region | CC |
GO:0014047 | glutamate secretion | BP |
GO:0016358 | dendrite development | BP |
GO:0008083 | growth factor activity | MF |
GO:0048839 | inner ear development | BP |
GO:0045666 | positive regulation of neuron differentiation | BP |
GO:0006916 | anti-apoptosis | BP |
GO:0042493 | response to drug | BP |
GO:0007411 | axon guidance | BP |
GO:0021675 | nerve development | BP |
GO:0048167 | regulation of synaptic plasticity | BP |
GO:0016023 | cytoplasmic membrane-bounded vesicle | CC |
GO:0001657 | ureteric bud development | BP |
GO:0043524 | negative regulation of neuron apoptosis | BP |
>gi|114326461|ref|NP_001041606.1| brain-derived neurotrophic factor isoform 2 precursor [Mus musculus] MTILFLTMVISYFGCMKAAPMKEVNVHGQGNLAYPGVRTHGTLESVNGPRAGSRGLTTTSLADTFEHVIE ELLDEDQKVRPNEENHKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGEL SVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQC RTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR |