Protein Information

ID 33
Name ATPase
Synonyms ATP7A; MK; ATPase; Cation transporting ATPase; ATP7A protein; ATPase Cu(2+) transporting alpha polypeptide; Copper pump 1; Copper transporting ATPase 1…

Compound Information

ID 183
Name lindane
CAS (1α,2α,3β,4α,5α,6β)-1,2,3,4,5,6-hexachlorocyclohexane

Reference

PubMed Abstract RScore(About this table)
7533627 Moreno MJ, Pellicer S, Marti A, Arenas JC, Fernandez-Otero MP: Effect of lindane on galactose and leucine transport in chicken enterocytes. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1994 Oct;109(2):159-66.
Lindane (gamma-hexachlorocyclohexane) influence on the in vitro intestinal transport of D-galactose and L-leucine has been studied in isolated chicken enterocytes. Animals were injected i.p. with 30 mg/kg b.w. of the pesticide over 7 days. Total uptake of D-galactose and L-leucine was significantly decreased by lindane action. There was no alteration in the non-mediated component, but the mediated transport was markedly inhibited in both cases. Furthermore, the exit of D-galactose across the basolateral membrane, as well as (Na (+)-K+)-ATPase activity, was significantly decreased in pesticide-treated chickens.
1(0,0,0,1)