| Name | PPAR |
|---|---|
| Synonyms | NR1C1; PPAR; PPAR alpha; PPARA; PPARalpha; Peroxisome proliferator activated receptor; Peroxisome proliferator activated receptor alpha; hPPAR… |
| Name | acrolein |
|---|---|
| CAS | 2-propenal |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20091025 | Mizukami S, Ichimura R, Kemmochi S, Taniai E, Shimamoto K, Ohishi T, Takahashi M, Mitsumori K, Shibutani M: Induction of GST-P-positive proliferative lesions facilitating lipid peroxidation with possible involvement of transferrin receptor up-regulation and ceruloplasmin down-regulation from the early stage of liver tumor promotion in rats. Arch Toxicol. 2010 Apr;84(4):319-31. Epub 2009 Dec 20. To estimate the involvement of oxidative stress responses to the promotion, immunolocalization of malondialdehyde and acrolein was similarly examined. |
0(0,0,0,0) | Details |
| 16413037 | Wung BS, Wu CC, Hsu MC, Hsieh CW: 15-Deoxy-Delta (12,14)-prostaglandin J (2) suppresses IL-6-induced STAT3 phosphorylation via electrophilic reactivity in endothelial cells. Life Sci. 2006 May 22;78(26):3035-42. Epub 2006 Jan 18. The electrophilic compound, acrolein, mimics the inhibition effect of 15d-PGJ (2). |
0(0,0,0,0) | Details |
| 20149621 | Zhu L, Liu Z, Feng Z, Hao J, Shen W, Li X, Sun L, Sharman E, Wang Y, Wertz K, Weber P, Shi X, Liu J: protects against oxidative damage by simultaneous activation of mitochondrial biogenesis and phase II detoxifying enzyme systems in retinal pigment epithelial cells. J Nutr Biochem. 2010 Feb 9. treatment simultaneously protected against acrolein-induced inhibition of nuclear factor-E2-related factor 2 (Nrf2) and peroxisome proliferator-activated receptor coactivator 1 alpha (PPARGC1alpha) in ARPE-19 cells. |
81(1,1,1,1) | Details |