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esfenvalerate

Identification (Source:EPA,EU)

ID	1617
Name	esfenvalerate
CAS	66230-04-4
IUPAC
Inchi	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1
CIPAC	481
EPA Code
Formula	C25H22ClNO3
SMILES	Clc1ccc(cc1)[C@H](C(=O)O[C@@H](C#N)c3cccc(Oc2ccccc2)c3)C(C)C
Status	Approved

Classification

Mode of Action	Contact and stomach action. Sodium channel modulator.
Pesticide Type	Insecticide
Chemical Group	Pyrethroid
Classification	pyrethroid ester insecticides

Properties (Source:PubChem)

Molecular Weight	419.90
Physical State	Amber solid
AlogP	6.564
H-Bond Donor	0
H-Bond Acceptor	4
Surface Area	405.51
Polar Surface Area	59.32

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	0.0065 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	0.0009 mg l-1
Aquatic invertebrates	Chronic	21 day	NOEC	0.000052 mg l-1
Birds	Short term dietary		LC50/LD50	> 5000 ppm
Birds	Acute		LD50	1312 mg kg-1
Earthworms	Acute	14 day	LD50	10.6 mg kg-1
Fish	Acute	96 hour	LC50	0.0001 mg l-1
Fish	Chronic	21 day	NOEC	0.00025 mg l-1
Honeybees	Acute	48 hour	LD50	0.06 μg bee-1
Mammals	Acute oral		LD50	7.9 mg kg-1
Mammals	Short term dietary		NOEL	88.5 mg kg-1
Sediment dwelling organisms	Acute	96 hour	LC50	0.00013 mg l-1
	Bio-concentration factor		BCF	3250
	Bio-concentration factor		CT50	Not available days

Related targets

Target Name	RScore (About this table)
sodium channel (protein family or complex)	85(1,1,1,5)	Details
hCE 2	82(1,1,1,2)	Details
androgen receptor	81(1,1,1,1)	Details
connexin 32	81(1,1,1,1)	Details
carboxylesterase 1	63(0,2,2,3)	Details
ha 1	31(0,1,1,1)	Details
cis 3	31(0,1,1,1)	Details
estrogen receptor	31(0,1,1,1)	Details
hCE 1	31(0,1,1,1)	Details
cytochrome P450 (protein family or complex)	31(0,1,1,1)	Details
Acetylcholinesterase	15(0,0,1,10)	Details

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