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methoxyfenozide

Identification (Source:EPA,EU)

ID	1436
Name	methoxyfenozide
CAS	161050-58-4
IUPAC
Inchi	InChI=1S/C22H28N2O3/c1-14-11-15(2)13-17(12-14)21(26)24(22(4,5)6)23-20(25)18-9-8-10-19(27-7)16(18)3/h8-13H,1-7H3,(H,23,25)
CIPAC	656
EPA Code
Formula	C22H28N2O3
SMILES	O=C(c1cc(cc(c1)C)C)N(NC(=O)c2cccc(OC)c2C)C(C)(C)C
Status	Approved

Classification

Mode of Action	A moulting accelerator that is an agonist of the hormone 20-hydroxyecdysone
Pesticide Type	Insecticide
Chemical Group	Diacylhydrazine
Classification	moulting hormone agonists

Properties (Source:PubChem)

Molecular Weight	368.47
Physical State	White powder
AlogP	4.45
H-Bond Donor	1
H-Bond Acceptor	3
Surface Area	395.27
Polar Surface Area	58.64

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	> 3.4 mg l-1
Aquatic crustaceans	Acute	96 hour	LC50	1.2 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	3.7 mg l-1
Aquatic invertebrates	Chronic	21 day	NOEC	0.39 mg l-1
Birds	Short term dietary		LC50/LD50	> 5620 mg/kg feed
Birds	Acute		LD50	> 2250 mg kg-1
Earthworms	Acute	14 day	LD50	> 607 mg kg-1
Fish	Acute	96 hour	LC50	> 4.2 mg l-1
Fish	Chronic	21 day	NOEC	2.4 mg l-1
Honeybees	Acute	48 hour	LD50	> 100 μg bee-1
Mammals	Acute oral		LD50	> 5000 mg kg-1
Mammals	Short term dietary		NOEL	> 10 mg kg-1
Sediment dwelling organisms	Chronic	28 day	NOEC, sediment	0.018 mg kg-1
	Bio-concentration factor		BCF	11
	Bio-concentration factor		CT50	Not available days

Related targets

Target Name	RScore (About this table)
retinoid X receptor (protein family or complex)	85(1,1,1,5)	Details
lipase	9(0,0,1,4)	Details
p65	8(0,0,1,3)	Details
P60	8(0,0,1,3)	Details
GAL4	6(0,0,0,6)	Details

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