@import"https://fonts.googleapis.com/css2?family=Inter:wght@400;500;600;700;800&display=swap";:root{--primary: #3b82f6;--primary-hover: #2563eb;--primary-light: #eff6ff;--secondary: #10b981;--accent: #f59e0b;--danger: #ef4444;--text-main: #0f172a;--text-sub: #64748b;--text-light: #94a3b8;--bg-page: #ffffff;--bg-subtle: #f8fafc;--border-light: #e2e8f0;--radius-md: 12px;--radius-lg: 16px;--shadow-sm: 0 1px 3px rgba(0, 0, 0, .1);--shadow-md: 0 4px 6px -1px rgba(0, 0, 0, .05), 0 2px 4px -1px rgba(0, 0, 0, .03);--shadow-lg: 0 10px 15px -3px rgba(0, 0, 0, .05), 0 4px 6px -2px rgba(0, 0, 0, .025);--shadow-xl: 0 20px 25px -5px rgba(0, 0, 0, .1), 0 10px 10px -5px rgba(0, 0, 0, .04)}body{margin:0;font-family:Inter,-apple-system,BlinkMacSystemFont,sans-serif;background-color:var(--bg-page);color:var(--text-main);line-height:1.6;-webkit-font-smoothing:antialiased}.app-layout{display:flex;flex-direction:column;min-height:100vh}.main-content{flex:1;width:100%;max-width:1400px;margin:0 auto;padding:0 24px 80px;box-sizing:border-box;z-index:10}.common-section-header{text-align:center;margin-bottom:60px;display:flex;flex-direction:column;align-items:center;max-width:800px;margin-left:auto;margin-right:auto}.common-section-title{font-family:Inter,sans-serif;font-size:2.25rem;font-weight:800;color:var(--text-main);margin:0 0 16px;letter-spacing:-.02em;line-height:1.2}.common-section-divider{width:60px;height:4px;background-color:var(--primary);border-radius:2px;margin-bottom:20px}.common-section-subtitle{font-size:1.1rem;color:var(--text-sub);line-height:1.6;font-weight:400;max-width:600px}.section-container{margin-bottom:100px}.overview-grid{display:grid;grid-template-columns:repeat(auto-fit,minmax(260px,1fr));gap:32px}.stat-card{background:#fff;border:1px solid var(--border-light);border-radius:var(--radius-lg);padding:40px 24px;text-align:center;display:flex;flex-direction:column;align-items:center;transition:all .3s cubic-bezier(.4,0,.2,1);position:relative}.stat-card:hover{transform:translateY(-8px);box-shadow:var(--shadow-xl);border-color:#bfdbfe}.stat-icon-wrapper{width:72px;height:72px;border-radius:50%;display:flex;align-items:center;justify-content:center;margin-bottom:24px;transition:transform .3s ease}.stat-number{font-size:2.5rem;font-weight:800;line-height:1;margin-bottom:12px;letter-spacing:-.02em;color:var(--text-main)}.stat-label{font-size:1.1rem;font-weight:700;color:var(--text-main);margin-bottom:8px}.stat-desc{font-size:.95rem;color:var(--text-sub);line-height:1.5}.steps-wrapper{position:relative}.steps-connector-line{position:absolute;top:16px;left:12%;right:12%;height:2px;background-image:linear-gradient(to right,#cbd5e1 50%,transparent 50%);background-size:16px 1px;background-repeat:repeat-x;z-index:0}.steps-container{display:grid;grid-template-columns:repeat(4,1fr);gap:32px;position:relative;z-index:1}.step-card{display:flex;flex-direction:column;align-items:center;text-align:center;padding:0 12px;position:relative}.step-badge{width:32px;height:32px;background:var(--secondary);color:#fff;border-radius:50%;font-weight:700;font-size:.9rem;display:flex;align-items:center;justify-content:center;margin-bottom:16px;box-shadow:0 0 0 10px #fff;z-index:2;position:relative}.step-icon{width:80px;height:80px;background:#fff;border-radius:20px;display:flex;align-items:center;justify-content:center;color:var(--primary);border:1px solid var(--border-light);box-shadow:var(--shadow-sm);margin-bottom:24px;transition:all .3s cubic-bezier(.4,0,.2,1)}.step-card:hover .step-icon{transform:translateY(-8px);box-shadow:var(--shadow-lg);border-color:var(--primary);color:var(--primary-hover)}.step-title{font-size:1.1rem;font-weight:700;color:var(--text-main);margin-bottom:8px}.step-desc{font-size:.95rem;color:var(--text-sub);line-height:1.5}@media(max-width:1024px){.steps-container{grid-template-columns:repeat(2,1fr);gap:48px 24px}.steps-connector-line{display:none}.step-badge{margin-bottom:12px;box-shadow:none}}@media(max-width:640px){.common-section-title{font-size:1.75rem}.common-section-subtitle{font-size:1rem}.overview-grid{grid-template-columns:1fr}.steps-container{grid-template-columns:1fr;gap:40px}.step-card{flex-direction:row;text-align:left;align-items:flex-start;gap:20px;padding:0}.step-badge{display:none}.step-icon{width:64px;height:64px;margin-bottom:0;flex-shrink:0}.step-title{margin-top:4px}}.auth-required-message{display:flex;flex-direction:column;align-items:center;justify-content:center;min-height:60vh;padding:40px 20px}.message-card{background:#fff;border-radius:20px;padding:48px;box-shadow:0 20px 60px #00000014;border:1px solid #e2e8f0;max-width:520px;width:100%;text-align:center;position:relative;overflow:hidden;transition:all .3s cubic-bezier(.4,0,.2,1)}.message-card:before{content:"";position:absolute;top:0;left:0;right:0;height:4px;background:linear-gradient(90deg,#3b82f6,#8b5cf6,#ec4899);animation:shimmer 3s ease-in-out infinite}@keyframes shimmer{0%,to{opacity:.8}50%{opacity:1}}.auth-icon-wrapper{display:inline-flex;align-items:center;justify-content:center;width:80px;height:80px;background:linear-gradient(135deg,#eff6ff,#dbeafe);border-radius:20px;margin-bottom:24px;box-shadow:0 8px 25px #3b82f626;transition:all .3s ease}.auth-icon-wrapper:hover{transform:scale(1.05);box-shadow:0 12px 35px #3b82f633}.auth-icon{color:#3b82f6}.auth-content h2{font-size:2rem;font-weight:800;color:#0f172a;margin:0 0 16px;letter-spacing:-.02em}.auth-content p{font-size:1.1rem;color:#64748b;margin:0 0 32px;line-height:1.6}.auth-features{display:flex;flex-direction:column;gap:16px;margin-bottom:32px;text-align:left}.feature-item{display:flex;align-items:center;gap:12px;padding:12px 16px;background:#f8fafc;border-radius:12px;border:1px solid #e2e8f0;transition:all .2s ease}.feature-item:hover{background:#eff6ff;border-color:#bfdbfe;transform:translate(4px)}.feature-icon{font-size:1.2rem;flex-shrink:0}.feature-item span:last-child{font-size:.9rem;color:#475569;font-weight:500}.auth-prompt-button{display:inline-flex;align-items:center;justify-content:center;gap:8px;width:100%;padding:16px 24px;background:#3b82f6;color:#fff;border:none;border-radius:12px;font-size:1rem;font-weight:600;cursor:pointer;transition:all .2s cubic-bezier(.4,0,.2,1);position:relative;overflow:hidden}.auth-prompt-button:before{content:"";position:absolute;top:0;left:-100%;width:100%;height:100%;background:linear-gradient(90deg,transparent,rgba(255,255,255,.2),transparent);transition:left .5s ease}.auth-prompt-button:hover:before{left:100%}.auth-prompt-button:hover:not(:disabled){background:#2563eb;transform:translateY(-2px);box-shadow:0 12px 35px #3b82f640}.auth-prompt-button:disabled{opacity:.6;cursor:not-allowed;transform:none;box-shadow:none}.button-arrow{transition:transform .2s ease}.auth-prompt-button:hover:not(:disabled) .button-arrow{transform:translate(2px)}@media(max-width:768px){.auth-required-message{min-height:50vh;padding:20px 16px}.message-card{padding:32px 24px;border-radius:16px}.auth-icon-wrapper{width:64px;height:64px;margin-bottom:20px}.auth-content h2{font-size:1.5rem}.auth-content p{font-size:1rem;margin-bottom:24px}.auth-features{gap:12px;margin-bottom:24px}.feature-item{padding:10px 14px}.auth-prompt-button{padding:14px 20px;font-size:.9rem}}.auth-modal-overlay{position:fixed;inset:0;background:#0006;-webkit-backdrop-filter:blur(4px);backdrop-filter:blur(4px);display:flex;align-items:center;justify-content:center;z-index:1000;animation:fadeIn .3s cubic-bezier(.4,0,.2,1)}@keyframes fadeIn{0%{opacity:0}to{opacity:1}}.auth-modal{background:#fff;border-radius:16px;padding:40px;max-width:440px;width:90%;box-shadow:0 20px 60px #0000001f;border:1px solid #e2e8f0;animation:slideUp .4s cubic-bezier(.4,0,.2,1);position:relative}@keyframes slideUp{0%{transform:translateY(20px);opacity:0}to{transform:translateY(0);opacity:1}}.close-button{position:absolute;top:20px;right:20px;background:transparent;border:1px solid #e2e8f0;font-size:1.2rem;cursor:pointer;color:#64748b;transition:all .2s cubic-bezier(.4,0,.2,1);padding:0;width:36px;height:36px;display:flex;align-items:center;justify-content:center;border-radius:8px}.close-button:hover{color:#0f172a;background-color:#f1f5f9;transform:scale(1.05)}.auth-header{margin-bottom:40px;text-align:center}.auth-header h2{font-size:2rem;font-weight:800;color:#0f172a;margin:0 0 12px;letter-spacing:-.02em}.auth-subtitle{font-size:1rem;color:#64748b;margin:0;line-height:1.5}.auth-form{display:flex;flex-direction:column;gap:20px;margin-bottom:32px}.form-group{display:flex;flex-direction:column}.form-group label{font-size:.9rem;font-weight:600;color:#0f172a;margin-bottom:8px}.form-group input{padding:14px 16px;border:1px solid #e2e8f0;border-radius:10px;font-size:.95rem;font-family:inherit;transition:all .2s cubic-bezier(.4,0,.2,1);background:#f8fafc}.form-group input:focus{outline:none;border-color:#3b82f6;background:#fff;box-shadow:0 0 0 3px #3b82f61a}.form-group input:disabled{background:#f1f5f9;cursor:not-allowed;opacity:.6}.form-group input::placeholder{color:#94a3b8}.error-message{background:#fef2f2;color:#dc2626;padding:14px 16px;border-radius:10px;font-size:.9rem;border-left:4px solid #dc2626;border:1px solid #fecaca}.submit-button{padding:14px 20px;background:#3b82f6;color:#fff;border:none;border-radius:10px;font-size:1rem;font-weight:600;cursor:pointer;transition:all .2s cubic-bezier(.4,0,.2,1);margin-top:12px;letter-spacing:.01em}.submit-button:hover:not(:disabled){background:#2563eb;box-shadow:0 8px 25px #3b82f640;transform:translateY(-2px)}.submit-button:disabled{opacity:.5;cursor:not-allowed;transform:none;box-shadow:none}.auth-footer{text-align:center;border-top:1px solid #e2e8f0;padding-top:24px}.auth-footer p{margin:0;font-size:.9rem;color:#64748b;line-height:1.5}.toggle-link{background:none;border:none;color:#3b82f6;font-weight:600;cursor:pointer;text-decoration:none;transition:all .2s cubic-bezier(.4,0,.2,1);padding:0;font-size:inherit;position:relative}.toggle-link:hover:not(:disabled){color:#2563eb;text-decoration:underline}.toggle-link:disabled{cursor:not-allowed;opacity:.5}@media(max-width:480px){.auth-modal{padding:32px 24px;max-width:95%;margin:20px}.auth-header h2{font-size:1.75rem}.auth-form{gap:16px}.form-group input{padding:12px 14px;font-size:.9rem}.submit-button{padding:12px 16px}}:root{--header-height: 80px;--primary-color: #3b82f6;--text-main: #0f172a;--text-secondary: #64748b;--bg-glass: rgba(255, 255, 255, .95);--shadow-sm: 0 1px 2px 0 rgba(0, 0, 0, .05)}.app-header{position:sticky;top:0;z-index:9999;width:100%;height:var(--header-height);background-color:var(--bg-glass);backdrop-filter:blur(12px);-webkit-backdrop-filter:blur(12px);border-bottom:1px solid rgba(226,232,240,.8)}.header-inner{max-width:1440px;margin:0 auto;height:100%;padding:0 32px;display:flex;align-items:center;justify-content:space-between}.logo-wrapper{display:flex;align-items:center;gap:12px;text-decoration:none;cursor:pointer}.logo-img{width:44px;height:44px;object-fit:contain;border-radius:8px}.logo-text{font-family:Inter,sans-serif;font-size:1.75rem;font-weight:800;color:#0f172a!important;letter-spacing:-.02em}.main-nav{position:absolute;left:50%;transform:translate(-50%)}.nav-items{display:flex;align-items:center;gap:40px;list-style:none;margin:0;padding:0}.nav-item{display:flex;align-items:center;gap:8px;text-decoration:none;color:var(--text-secondary);font-weight:600;font-size:1rem;transition:all .2s;padding:8px 16px;border-radius:8px}.nav-item:hover{color:var(--primary-color);background-color:#3b82f60d}.nav-item.active{color:var(--primary-color);background-color:#3b82f61a}.header-actions{display:flex;align-items:center}.user-menu-wrapper{position:relative}.user-profile-btn{display:flex;align-items:center;gap:12px;background:transparent;border:1px solid transparent;padding:4px 12px 4px 4px;border-radius:40px;cursor:pointer;transition:all .2s}.user-profile-btn:hover{background-color:#f1f5f9;border-color:#e2e8f0}.avatar-circle{width:36px;height:36px;border-radius:50%;background:linear-gradient(135deg,#3b82f6,#2563eb);color:#fff;font-weight:700;display:flex;align-items:center;justify-content:center;font-size:1rem}.user-identifier{font-size:.95rem;font-weight:600;color:#0f172a;white-space:nowrap;display:inline-block}.dropdown-menu{position:absolute;top:calc(100% + 12px);right:0;width:240px;background:#fff;border:1px solid #e2e8f0;border-radius:12px;box-shadow:0 10px 25px -5px #0000001a;padding:8px;z-index:10000}.dropdown-info{padding:12px 16px;background-color:#f8fafc;border-radius:8px;margin-bottom:8px}.info-email{font-weight:600;color:#0f172a;word-break:break-all}.dropdown-action{width:100%;display:flex;align-items:center;gap:10px;padding:10px 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#1e293b;font-size:.85rem}.footer-content{max-width:1400px;margin:0 auto;padding:32px 24px 24px;display:grid;grid-template-columns:repeat(4,1fr);gap:20px;justify-items:center;text-align:center}.footer-column{display:flex;flex-direction:column;align-items:center;width:100%}.footer-column.brand-column{justify-content:center;min-height:120px}.footer-column:not(.brand-column){justify-content:flex-start}.footer-column h4{color:#f8fafc;font-size:.8rem;font-weight:700;margin:0 0 12px;text-transform:uppercase;letter-spacing:.05em}.footer-logo{display:flex;align-items:center;gap:8px;margin-bottom:8px}.footer-logo img{width:32px;height:32px;border-radius:6px;background:#fff;padding:2px}.footer-logo .logo-text{font-size:1.25rem;font-weight:800;color:#fff!important}.brand-desc{font-size:.8rem;line-height:1.5;color:#64748b;margin:0 0 12px;max-width:240px}.version-tag{background:#ffffff1a;color:#cbd5e1;padding:2px 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20px}}@media(max-width:640px){.footer-content{grid-template-columns:1fr;gap:32px;padding:32px 20px}}.disease-selector{position:relative;width:100%}.search-form{display:flex;gap:8px;border:1px solid #e2e8f0;border-radius:12px;padding:6px;background-color:#fff;box-shadow:0 4px 20px #0000000d;transition:all .2s ease;margin-bottom:24px}.search-form:focus-within{border-color:#3b82f6;box-shadow:0 4px 20px #3b82f626}.search-input{flex:1;padding:12px 16px;border:none;border-radius:8px;font-size:1rem;outline:none;color:#1e293b;background:transparent}.search-input::placeholder{color:#94a3b8}.search-button{padding:10px 24px;background:#3b82f6;color:#fff;border:none;border-radius:8px;font-size:.95rem;font-weight:600;cursor:pointer;transition:all .2s ease}.search-button:hover:not(:disabled){background:#2563eb;transform:translateY(-1px)}.search-button:disabled{background-color:#cbd5e1;cursor:not-allowed}.disease-list{position:absolute;top:calc(100% + 8px);left:0;right:0;background:#fff;border:1px solid #e2e8f0;border-radius:12px;max-height:300px;overflow-y:auto;z-index:100;margin:0;padding:8px 0;list-style:none;box-shadow:0 10px 25px -5px #0000001a}.disease-item{padding:10px 16px;cursor:pointer;color:#334155;font-size:.95rem;transition:background .1s}.disease-item:hover,.disease-item.selected{background:#eff6ff;color:#3b82f6}.examples-section{display:flex;flex-direction:column;align-items:center;gap:12px;width:100%}.examples-label{margin:0!important;font-size:.85rem;color:#94a3b8;font-weight:600;text-transform:uppercase;letter-spacing:.05em;display:flex;align-items:center;gap:6px}.examples-list{display:flex;flex-wrap:wrap;justify-content:center;gap:12px;width:100%;margin:0!important;padding:0!important}.example-button{display:inline-flex;align-items:center;gap:8px;padding:8px 16px;background:#fff;border:1px solid #e2e8f0;border-radius:50px;color:#64748b;font-size:.85rem;font-weight:500;font-family:inherit;cursor:pointer;transition:all .2s cubic-bezier(.4,0,.2,1);box-shadow:0 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#3b82f626}.topk-value-badge{background-color:transparent;color:#3b82f6;font-family:Inter,sans-serif;font-weight:800;font-size:1rem;padding:0;border:none;min-width:24px;text-align:right}@media(max-width:640px){.topk-container{flex-direction:column;align-items:stretch;gap:8px}.topk-header{justify-content:space-between}}.drug-card{background-color:#fff;border:1px solid #e2e8f0;border-radius:12px;padding:12px 16px;cursor:pointer;transition:all .2s cubic-bezier(.4,0,.2,1);position:relative;overflow:hidden}.drug-card:hover{transform:translateY(-2px);box-shadow:0 4px 12px #94a3b826;border-color:#cbd5e1}.drug-card.selected{background-color:#f0f9ff;border-color:#3b82f6;box-shadow:0 0 0 1px #3b82f6 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#3b82f626}.search-icon-wrapper{padding-left:16px;padding-right:12px;display:flex;align-items:center}.fusion-input{flex:1;border:none;outline:none;font-size:1rem;color:#1e293b;background:transparent;padding:10px 0}.fusion-button{background:#3b82f6;color:#fff;border:none;padding:10px 24px;border-radius:6px;font-size:1rem;font-weight:500;cursor:pointer;transition:all .2s;display:flex;align-items:center;gap:6px;margin-right:2px}.fusion-button:hover:not(:disabled){background:#2563eb}.fusion-button:disabled{background:#cbd5e1;cursor:not-allowed}.search-examples{display:flex;flex-wrap:wrap;justify-content:center;align-items:center;gap:12px;margin-top:8px}.example-label{font-size:.85rem;color:#64748b;font-weight:600;display:flex;align-items:center;gap:4px}.example-pill{background:#f8fafc;border:1px solid #e2e8f0;padding:4px 12px;border-radius:4px;font-size:.8rem;color:#475569;cursor:pointer;transition:all 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