ferritin heavy chain

General Information (Source: NCBI Gene,UniProt)

Text mining Term	ferritin heavy chain
UniProt ID	FRIH_MOUSE
Name	Ferritin H subunit Ferritin heavy chain
Gene Names	Fth1 Synonyms:Fth
Taxonomy	Mus musculus

General annotation

Function	Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.
Subcellular location

Gene Ontology

GO:0006879	cellular iron ion homeostasis	BP
GO:0008285	negative regulation of cell proliferation	BP
GO:0005739	mitochondrion	CC
GO:0006826	iron ion transport	BP
GO:0004322	ferroxidase activity	MF
GO:0008199	ferric iron binding	MF
GO:0006955	immune response	BP

Sequence

>gi|6753912|ref|NP_034369.1| ferritin heavy chain [Mus musculus]
MTTASPSQVRQNYHQDAEAAINRQINLELYASYVYLSMSCYFDRDDVALKNFAKYFLHQSHEEREHAEKL
MKLQNQRGGRIFLQDIKKPDRDDWESGLNAMECALHLEKSVNQSLLELHKLATDKNDPHLCDFIETYYLS
EQVKSIKELGDHVTNLRKMGAPEAGMAEYLFDKHTLGHGDES

Database Cross Reference

Ensembl Gene	ENSMUST00000025563
UniGene	Mm.1776
PDB
RefSeq	NP_034369.1
Pfam	PF00210

PTID

ferritin heavy chain

General Information (Source: NCBI Gene,UniProt)

General annotation

Gene Ontology

Sequence

Options for BLAST

Database:

Set subsequence:(optional):

Optional parameters:

Database Cross Reference