Acetylcholinesterase

General Information (Source: NCBI Gene,UniProt)

Text mining Term Acetylcholinesterase
UniProt ID Q543Z1_MOUSE
Name Acetylcholinesterase
Gene Names Ache
Taxonomy Mus musculus

General annotation

Function
Subcellular location

Gene Ontology

GO:0007271 synaptic transmission, cholinergic BP
GO:0045212 neurotransmitter receptor biosynthetic process BP
GO:0005788 endoplasmic reticulum lumen CC
GO:0060041 retina development in camera-type eye BP
GO:0009986 cell surface CC
GO:0030424 axon CC
GO:0042734 presynaptic membrane CC
GO:0019695 choline metabolic process BP
GO:0048814 regulation of dendrite morphogenesis BP
GO:0045211 postsynaptic membrane CC
GO:0003990 acetylcholinesterase activity MF
GO:0030425 dendrite CC
GO:0007416 synapse assembly BP
GO:0050770 regulation of axonogenesis BP
GO:0005615 extracellular space CC
GO:0005886 plasma membrane CC
GO:0051262 protein tetramerization BP
GO:0006581 acetylcholine catabolic process BP
GO:0043621 protein self-association MF
GO:0005605 basal lamina CC
GO:0001919 regulation of receptor recycling BP
GO:0031623 receptor internalization BP
GO:0004091 carboxylesterase activity MF
GO:0031594 neuromuscular junction CC

Sequence

>gi|13928664|ref|NP_033729.1| acetylcholinesterase precursor [Mus musculus]
MRPPWYPLHTPSLAFPLLFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPGGPVSAFLGIPFAE
PPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPA
SPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLA
LQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRAT
LLARLVGCPPGGAGGNDTELIACLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPEALINTG
DFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPE
DPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPL
DPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSPQWPPYTTAAQQYVSLNLKPLEVRRGLRAQTC
AFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQERCSDL

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Mm.255464
PDB
RefSeq NP_033729.1
Pfam PF00135
PF08674