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biphenyl

Identification (Source:EPA,EU)

ID	477
Name	biphenyl
CAS	92-52-4
IUPAC	biphenyl
Inchi	InChI=1S/C12H10/c1-3-7-11(8-4-1)12-9-5-2-6-10-12/h1-10H
CIPAC	None allocated
EPA Code	017002
Formula	C12H10
SMILES	c1cc(ccc1)c2ccccc2
Status	Not Approved

Classification

Mode of Action	Inhibits sporulation
Pesticide Type	Fungicide
Chemical Group	Aromatic hydrocarbon
Classification	aromatic fungicides

Properties (Source:PubChem)

Molecular Weight	154.21
Physical State	Colourless crystals
AlogP	3.348
H-Bond Donor	0
H-Bond Acceptor	0
Surface Area	153.37
Polar Surface Area	0.0

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	1.3 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	2.38 mg l-1
Aquatic invertebrates	Chronic	21 day	NOEC	0.17 mg l-1
Fish	Acute	96 hour	LC50	1.5 mg l-1
Mammals	Acute oral		LD50	2140 mg kg-1
	Bio-concentration factor		CT50	Not available days
	Bio-concentration factor		BCF	2700

Related targets

Target Name	RScore (About this table)
Fatty acid amide hydrolase	456(2,10,11,51)	Details
peroxisome proliferator activated receptor gamma	311(2,5,6,56)	Details
angiotensin II	356(2,3,3,166)	Details
anticholinesterase	204(2,3,3,14)	Details
5 lipoxygenase	200(2,3,3,10)	Details
cytochrome P450 (protein family or complex)	190(2,2,4,20)	Details
P gp	182(2,2,3,17)	Details
cyclooxygenase 1	162(2,2,2,2)	Details
transthyretin	149(1,3,3,9)	Details
Factor Xa	147(1,3,3,7)	Details
Ah receptor	141(1,2,2,31)	Details
mGlu2	124(1,2,2,14)	Details
squalene synthase	121(1,2,2,11)	Details
dihydrofolate reductase	119(1,2,2,9)	Details
carbonic anhydrase	118(1,2,2,8)	Details
Growth hormone secretagogues	118(1,2,2,8)	Details
bradykinin	113(1,2,2,3)	Details
lipase	90(1,1,1,10)	Details
angiotensin converting enzyme 2	89(1,1,1,9)	Details
BLT2	87(1,1,1,7)	Details
NK1	84(1,1,1,4)	Details
beta catenin	84(1,1,1,4)	Details
glutamate receptors (protein family or complex)	83(1,1,1,3)	Details
MMP 2	82(1,1,1,2)	Details
MP2	82(1,1,1,2)	Details
microsomal triglyceride transfer protein	81(1,1,1,1)	Details
matrix metalloproteinase 13	81(1,1,1,1)	Details
lipase a	81(1,1,1,1)	Details
p38	141(0,4,4,21)	Details
p38alpha	131(0,4,4,11)	Details
estrogen receptors	110(0,3,3,20)	Details
beta 3 adrenergic receptor	97(0,3,3,7)	Details
peroxisome proliferator activated receptor alpha	96(0,2,2,36)	Details
albumin	89(0,2,2,29)	Details
yl 1	86(0,2,6,6)	Details
5 HT1B receptor	80(0,2,2,20)	Details
gamma secretase (protein family or complex)	70(0,2,3,5)	Details
MCH1R	70(0,2,2,10)	Details
Ghrelin receptor	67(0,2,2,7)	Details
transferase	67(0,2,2,7)	Details
acetylcholine receptor (protein family or complex)	65(0,2,2,5)	Details
trypsin like serine protease	62(0,2,2,2)	Details
eta 1	62(0,2,2,2)	Details
Tyrosinase	65(0,1,1,35)	Details
NMDA receptors (protein family or complex)	50(0,1,1,20)	Details
NK 1 receptor	45(0,1,1,15)	Details
histone deacetylases (protein family or complex)	43(0,1,1,13)	Details
HDAC	42(0,1,1,12)	Details
cycloxygenase 2	41(0,1,1,11)	Details
dihydroorotate dehydrogenase	38(0,1,1,8)	Details
DP2	36(0,1,1,6)	Details
protein kinase B	35(0,1,1,5)	Details
5 HT 1A	35(0,1,1,5)	Details
G protein	35(0,1,1,5)	Details
cyclin dependent kinase (protein family or complex)	35(0,1,1,5)	Details
fibronectin	35(0,1,1,5)	Details
S1P	34(0,1,1,4)	Details
5 HT2B	34(0,1,1,4)	Details
Tcf 4	34(0,1,1,4)	Details
muscles	34(0,1,1,4)	Details
C10	33(0,1,1,3)	Details
cytochrome P450 1B1	33(0,1,1,3)	Details
bombesin receptor subtype 3	33(0,1,1,3)	Details
glycine receptor (protein family or complex)	33(0,1,1,3)	Details
alpha1 adrenoceptor (protein family or complex)	32(0,1,1,2)	Details
guanylate cyclase	32(0,1,1,2)	Details
ferredoxin reductase	32(0,1,1,2)	Details
cholecystokinin	32(0,1,1,2)	Details
dipeptidyl peptidase IV	32(0,1,1,2)	Details
MAP kinase	32(0,1,1,2)	Details
aggrecanase 1	32(0,1,1,2)	Details
CHK1	32(0,1,1,2)	Details
small G protein	31(0,1,1,1)	Details
Pr 3	31(0,1,1,1)	Details
thyroid hormone receptor (protein family or complex)	31(0,1,1,1)	Details
steroid sulfatase	31(0,1,1,1)	Details
Nerve growth factor	31(0,1,1,1)	Details
bcl 2	182(0,0,1,177)	Details
Bcl xL	66(0,0,0,66)	Details
mcl 1	56(0,0,0,56)	Details
FRAP	46(0,0,0,46)	Details
catalase	34(0,0,1,29)	Details
Cathepsin K	34(0,0,0,34)	Details
superoxide dismutase	33(0,0,0,33)	Details
caspase 3	32(0,0,0,32)	Details
AT1	27(0,0,0,27)	Details
vascular endothelial growth factor	26(0,0,1,21)	Details
CYP1A1	26(0,0,2,16)	Details
caspase (protein family or complex)	23(0,0,0,23)	Details
mitogen activated protein kinase (protein family or complex)	22(0,0,0,22)	Details
cytochrome c	22(0,0,0,22)	Details
tumor necrosis factor	22(0,0,0,22)	Details
TRAIL	21(0,0,0,21)	Details
adiponectin	20(0,0,1,15)	Details
CYP17	20(0,0,0,20)	Details
EGFR	18(0,0,0,18)	Details
Acetylcholinesterase	17(0,0,0,17)	Details
BTG3	16(0,0,1,11)	Details
neurokinin 1	16(0,0,0,16)	Details
ROCK1	15(0,0,0,15)	Details
glutathione S transferase	15(0,0,1,10)	Details
Bcl w	14(0,0,0,14)	Details
estrogen receptor beta	14(0,0,2,4)	Details
TRPV1	14(0,0,0,14)	Details
IL 1beta	13(0,0,0,13)	Details
PC 3	13(0,0,0,13)	Details
sodium iodide symporter	13(0,0,2,3)	Details
intercellular adhesion molecule 1	13(0,0,0,13)	Details
CDK4	12(0,0,1,7)	Details
xanthine oxidase	12(0,0,0,12)	Details
PI3K	11(0,0,0,11)	Details
alanine aminotransferase	11(0,0,0,11)	Details
ERK1	11(0,0,0,11)	Details
interleukin 6	11(0,0,0,11)	Details
myeloperoxidase	10(0,0,0,10)	Details
CYP3A	10(0,0,0,10)	Details
calcium channel (protein family or complex)	10(0,0,0,10)	Details
connective tissue growth factor	9(0,0,0,9)	Details
cyclin D1	9(0,0,0,9)	Details
chemokine	9(0,0,0,9)	Details
5 HT 2A	9(0,0,0,9)	Details
Lipoxygenase (protein family or complex)	9(0,0,0,9)	Details
Aurora A	9(0,0,0,9)	Details
cytokeratin 18	9(0,0,0,9)	Details

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