piperazine

Identification (Source:EPA,EU)

ID 1819
Name piperazine
CAS 110-85-0
IUPAC piperazine
Inchi InChI=1S/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H2
CIPAC
EPA Code
Formula C4H10N2
SMILES N1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
Status Not Available

Classification

Mode of Action
Pesticide Type
Chemical Group
Classification Miscellaneous

Properties (Source:PubChem)

Molecular Weight 86.1356
Physical State
AlogP -0.795
H-Bond Donor 2
H-Bond Acceptor 2
Surface Area 95.21
Polar Surface Area 24.06

Structure



ChemMapper Search Option (Docunmentation of ChemMapper)

3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Related targets

Target Name RScore (About this table)
5 HT1A 4389(30,72,72,729) Details
5 HT 2A 1856(13,31,31,276) Details
5 HT2C 1558(10,23,23,368) Details
dopamine transporter 1071(9,18,19,76) Details
5 HT1B 823(6,13,13,133) Details
5 HT transporter 598(5,9,9,78) Details
NR2D 556(5,9,10,31) Details
5 HT7 589(4,11,11,59) Details
melanocortin 4 receptor 541(4,10,11,36) Details
NMDA receptor (protein family or complex) 701(3,16,16,71) Details
Fatty acid amide hydrolase 448(3,9,9,28) Details
beta secretase 376(3,7,7,16) Details
serotonin receptor 340(3,5,5,40) Details
estrogen receptor 288(3,4,4,18) Details
NR2C 284(3,4,4,14) Details
Mu opioid receptor 276(3,4,4,6) Details
MMP 13 275(3,4,4,5) Details
CCR5 549(2,14,14,29) Details
transient receptor potential vanilloid 1 308(2,6,6,28) Details
5 HT 2B 322(2,5,5,72) Details
phosphodiesterase 237(2,4,4,17) Details
CYP3A4 240(2,3,3,50) Details
VR1 199(2,3,3,9) Details
TRPM8 194(2,2,3,29) Details
5 hydroxytryptamine receptor (protein family or complex) 194(2,2,3,29) Details
Acetylcholinesterase 176(2,2,2,16) Details
NK 1 173(2,2,2,13) Details
CYP2D6 270(1,6,7,35) Details
5 HT 3 228(1,4,4,58) Details
Ca II 212(1,4,4,42) Details
NR2B 206(1,4,5,31) Details
cytochrome P450 (protein family or complex) 192(1,4,4,22) Details
alpha2 adrenoceptor (protein family or complex) 192(1,4,4,22) Details
bradykinin 163(1,3,4,18) Details
dopamine D2 receptor 157(1,3,3,17) Details
NR2A 155(1,3,3,15) Details
protein kinase C (protein family or complex) 152(1,3,3,12) Details
benzodiazepine receptor (protein family or complex) 146(1,3,3,6) Details
somatostatin 141(1,2,2,31) Details
calcium channel (protein family or complex) 137(1,2,3,22) Details
PDE5 126(1,2,2,16) Details
histone deacetylase (protein family or complex) 118(1,2,2,8) Details
CA III 118(1,2,2,8) Details
integrin 117(1,2,2,7) Details
kappa opioid receptor 116(1,2,2,6) Details
histamine H3 receptors 115(1,2,2,5) Details
transferase 115(1,2,2,5) Details
IRK1 113(1,2,2,3) Details
GHSR 113(1,2,2,3) Details
G protein 118(1,1,1,38) Details
P glycoprotein 105(1,1,1,25) Details
thrombin 96(1,1,1,16) Details
DPP IV 95(1,1,1,15) Details
connective tissue growth factor 95(1,1,2,10) Details
TNF alpha 94(1,1,1,14) Details
5 HT4 94(1,1,1,14) Details
ATPase 92(1,1,1,12) Details
complex I 91(1,1,1,11) Details
delta opioid receptor 90(1,1,1,10) Details
bcl 2 88(1,1,1,8) Details
PLA2 87(1,1,1,7) Details
norepinephrine transporter 87(1,1,1,7) Details
calmodulin 86(1,1,1,6) Details
TRPA1 85(1,1,1,5) Details
GPCR 85(1,1,1,5) Details
brains 85(1,1,1,5) Details
ubiquitin 85(1,1,1,5) Details
HERG 85(1,1,1,5) Details
progelatinase 85(1,1,1,5) Details
beta glucuronidase 84(1,1,1,4) Details
Y5 receptors 84(1,1,1,4) Details
MMP 9 84(1,1,1,4) Details
extracellular signal regulated kinase 1 84(1,1,1,4) Details
Myosin 83(1,1,1,3) Details
p38 MAP kinase 83(1,1,1,3) Details
cathepsin B 82(1,1,1,2) Details
N acetyltransferase 82(1,1,1,2) Details
MT 4 82(1,1,1,2) Details
myoglobin 82(1,1,1,2) Details
plasminogen activator inhibitor 1 82(1,1,1,2) Details
soluble epoxide hydrolase 82(1,1,1,2) Details
prion proteins 81(1,1,1,1) Details
NADH dehydrogenase subunit 2 81(1,1,1,1) Details
SN2 81(1,1,1,1) Details
ACC1 81(1,1,1,1) Details
A2a 81(1,1,1,1) Details
yl 1 294(0,9,10,19) Details
catechol O methyltransferase 107(0,3,3,17) Details
liver carboxylesterase 103(0,3,3,13) Details
5 HT1D 101(0,3,3,11) Details
CYP1A2 80(0,2,2,20) Details
androgen receptor 75(0,2,3,10) Details
Cl 2 75(0,2,3,10) Details
neurokinin 1 73(0,2,2,13) Details
INDO 73(0,2,2,13) Details
alpha adrenoceptor 71(0,2,2,11) Details
CB1 69(0,2,2,9) Details
neurokinin 1 receptors 69(0,2,2,9) Details
angiotensin II 68(0,2,2,8) Details
suppressor of cytokine signaling 68(0,2,3,3) Details
Adenosine A2A receptor 68(0,2,2,8) Details
prodynorphin 67(0,2,2,7) Details
cytochrome c 65(0,2,2,5) Details
acetylcholine receptors (protein family or complex) 65(0,2,2,5) Details
metalloproteinase 64(0,2,2,4) Details
NK1 63(0,2,2,3) Details
TNF alpha converting enzyme 62(0,2,2,2) Details
Mops 62(0,2,2,2) Details
protein kinase C inhibitor 1 62(0,2,2,2) Details
CGRP 55(0,1,1,25) Details
G protein coupled receptors 49(0,1,1,19) Details
5 HT 5 46(0,1,2,11) Details
Factor Xa 44(0,1,1,14) Details
vascular endothelial growth factor 43(0,1,1,13) Details
sodium channel (protein family or complex) 42(0,1,2,7) Details
nNOS 41(0,1,1,11) Details
interleukin 1beta 40(0,1,1,10) Details
5 HT 1F 39(0,1,1,9) Details
protein kinase A (protein family or complex) 39(0,1,1,9) Details
GABA receptor (protein family or complex) 38(0,1,2,3) Details
C3 C5 37(0,1,2,2) Details
alpha 2C adrenoceptors 37(0,1,1,7) Details
prolyl dipeptidase DPP8 37(0,1,1,7) Details
transferrin 37(0,1,1,7) Details
Cathepsin K 37(0,1,1,7) Details
CYP2C19 36(0,1,1,6) Details
Ho 1 36(0,1,1,6) Details
HDAC 36(0,1,1,6) Details
NK 2 36(0,1,1,6) Details
CCR3 36(0,1,1,6) Details
phospholipase C 35(0,1,1,5) Details
PAR2 35(0,1,1,5) Details
MT 2 35(0,1,1,5) Details
sorbitol dehydrogenase 35(0,1,1,5) Details
demethylase 35(0,1,1,5) Details
p38 35(0,1,1,5) Details
indol 1 34(0,1,1,4) Details
HSD1 34(0,1,1,4) Details
cAMP response element binding protein 34(0,1,1,4) Details
phospholipase D (protein family or complex) 34(0,1,1,4) Details
Aurora A 34(0,1,1,4) Details
urotensin II receptor 33(0,1,1,3) Details
Tat 1 33(0,1,1,3) Details
CYP2C9 33(0,1,1,3) Details
CD4 33(0,1,1,3) Details
HDAC6 33(0,1,1,3) Details
VLA 4 33(0,1,1,3) Details
SPBP 33(0,1,1,3) Details
CXCR3 33(0,1,1,3) Details
stearoyl CoA desaturase 33(0,1,1,3) Details
apoprotein 33(0,1,1,3) Details
JNK3 33(0,1,1,3) Details
Cytochrome c oxidase (protein family or complex) 33(0,1,1,3) Details
AT1 32(0,1,1,2) Details
cyclin dependent kinase (protein family or complex) 32(0,1,1,2) Details
ML7 32(0,1,1,2) Details
c Jun N terminal kinase (protein family or complex) 32(0,1,1,2) Details
TRAM 32(0,1,1,2) Details
adenosine A2B receptors 32(0,1,1,2) Details
MMP 1 32(0,1,1,2) Details
chloride channel (protein family or complex) 32(0,1,1,2) Details
MRLC2 32(0,1,1,2) Details
Nle 32(0,1,1,2) Details
ORL1 32(0,1,1,2) Details
enkephalin 32(0,1,1,2) Details
PAPP a 31(0,1,1,1) Details
ERK2 31(0,1,1,1) Details
hand 1 31(0,1,1,1) Details
phosphodiesterases (protein family or complex) 31(0,1,1,1) Details
alpha lactalbumin 31(0,1,1,1) Details
cholecystokinin 1 receptor 31(0,1,1,1) Details
CA XIII 31(0,1,1,1) Details
HT2A 31(0,1,1,1) Details
myosin light chain kinase 31(0,1,1,1) Details
TERT 31(0,1,1,1) Details
protein disulfide isomerase 31(0,1,1,1) Details
mark 4 31(0,1,1,1) Details
FLT3 65(0,0,0,65) Details
Ghrelin 22(0,0,0,22) Details
albumin 21(0,0,2,11) Details
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