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EPN

Identification (Source:EPA,EU)

ID	1567
Name	EPN
CAS	2104-64-5
IUPAC
Inchi	InChI=1S/C14H15O2PS/c1-2-15-17(18,14-11-7-4-8-12-14)16-13-9-5-3-6-10-13/h3-12H,2H2,1H3
CIPAC	302
EPA Code	041801
Formula	C14H14NO4PS
SMILES	S=P(Oc1ccc(cc1)[N+]([O-])=O)(OCC)c2ccccc2
Status	Not Approved

Classification

Mode of Action	Non-systemic with contact and stomach action, works by cholinesterase inhibition
Pesticide Type	Insecticide, Acaricide
Chemical Group	Organophosphate
Classification	phosphonothioate insecticides phenyl phenylphosphonothioate insecticides

Properties (Source:PubChem)

Molecular Weight	323.30
Physical State	Yellow crystals
AlogP	4.082
H-Bond Donor	0
H-Bond Acceptor	3
Surface Area	256.44
Polar Surface Area	60.36

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Aquatic crustaceans	Acute	96 hour	LC50	0.003 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	0.00006 mg l-1
Birds	Acute		LD50	289 mg kg-1
Fish	Acute	96 hour	LC50	0.110 mg l-1
Mammals	Acute oral		LD50	14 mg kg-1

Related targets

Target Name	RScore (About this table)
butyrylcholinesterase	150(1,2,5,25)	Details
cytochrome P450 (protein family or complex)	93(1,1,1,13)	Details
aminopeptidase	81(1,1,1,1)	Details
mitogen activated protein kinase (protein family or complex)	81(1,1,1,1)	Details
Acetylcholinesterase	56(0,1,1,26)	Details
interleukin 6	38(0,1,2,3)	Details
ERK1	34(0,1,1,4)	Details
epn 1	32(0,1,1,2)	Details
rheumatoid factor	31(0,1,1,1)	Details
C type lectin	25(0,0,0,25)	Details
estradiol receptor	14(0,0,0,14)	Details
C type lectins (protein family or complex)	13(0,0,0,13)	Details
DC SIGN	13(0,0,0,13)	Details
endocrine gland derived vascular endothelial growth factor	13(0,0,0,13)	Details
APPI	13(0,0,2,3)	Details
Substance P	12(0,0,2,2)	Details
neurotoxic esterase	12(0,0,0,12)	Details
RIZ1	11(0,0,0,11)	Details
NeuroD1	10(0,0,0,10)	Details
Langerin	9(0,0,0,9)	Details
Aurora B	9(0,0,0,9)	Details
calcitonin	8(0,0,0,8)	Details
Mannose Binding Lectin	8(0,0,0,8)	Details
TEPP	7(0,0,1,2)	Details
CEase	7(0,0,0,7)	Details
epiphycan	7(0,0,1,2)	Details
biglycan	7(0,0,1,2)	Details
asporin	6(0,0,1,1)	Details
chromogranin A	6(0,0,0,6)	Details
dectin 2	6(0,0,0,6)	Details
parvalbumin	6(0,0,0,6)	Details
tryptophan pyrrolase	6(0,0,1,1)	Details
fibromodulin	6(0,0,1,1)	Details
lumican	6(0,0,1,1)	Details
vascular endothelial growth factor	5(0,0,0,5)	Details
c jun	5(0,0,0,5)	Details
cytochrome c	5(0,0,0,5)	Details
beta glucuronidase	5(0,0,0,5)	Details
Egasyn	5(0,0,0,5)	Details
PC3	5(0,0,0,5)	Details
PK2	5(0,0,0,5)	Details
tryptophan hydroxylase 2	5(0,0,0,5)	Details

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