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carbon tetrachloride

Identification (Source:EPA,EU)

ID	1392
Name	carbon tetrachloride
CAS	56-23-5
IUPAC
Inchi	InChI=1S/CCl4/c2-1(3,4)5
CIPAC	642
EPA Code	016501
Formula	CCl4
SMILES	C(Cl)(Cl)(Cl)Cl
Status	Not Available

Classification

Mode of Action	Interferes with transmissions of nerve impulses across axons disrupting primarily the central nervous system
Pesticide Type	Insecticide, Fumigant, Other product constituent
Chemical Group	Organochlorine
Classification	fumigant insecticides

Properties (Source:PubChem)

Molecular Weight	153.8
Physical State	Clear, colourless, volatile liquid
AlogP	3.584
H-Bond Donor	0
H-Bond Acceptor	0
Surface Area	123.92
Polar Surface Area	0.0

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Aquatic invertebrates	Acute	48 hour	EC50	29 mg l-1
Earthworms	Acute	14 day	LD50	160 mg kg-1
Fish	Acute	96 hour	LC50	43 mg l-1
Mammals	Acute oral		LD50	2821 mg kg-1
	Bio-concentration factor		CT50	Not available days
	Bio-concentration factor		BCF	30

Related targets

Target Name	RScore (About this table)
CYP2E1	518(3,8,10,118)	Details
albumin	425(3,4,10,125)	Details
heme oxygenase 1	389(3,4,10,89)	Details
col1A2	297(3,4,5,22)	Details
cytochrome P450 (protein family or complex)	314(2,5,8,49)	Details
superoxide dismutase	428(2,4,15,153)	Details
Aldehyde dehydrogenases (protein family or complex)	171(2,2,3,6)	Details
IL 10	220(1,3,3,80)	Details
alkaline phosphatase	258(1,2,10,108)	Details
IL 6	246(1,2,10,96)	Details
CD44	134(1,2,3,19)	Details
CB2	119(1,2,2,9)	Details
L17	118(1,2,2,8)	Details
Hepatocyte growth factor	131(1,1,2,46)	Details
STAT3	126(1,1,3,36)	Details
matrix metalloproteinase 2	113(1,1,1,33)	Details
adiponectin	107(1,1,3,17)	Details
mitogen activated protein kinase (protein family or complex)	106(1,1,1,26)	Details
AP 1 (protein family or complex)	105(1,1,2,20)	Details
c jun	104(1,1,2,19)	Details
senescence marker protein 30	104(1,1,2,19)	Details
FSAP	99(1,1,2,14)	Details
endothelial nitric oxide synthase	99(1,1,3,9)	Details
arginase	98(1,1,3,8)	Details
uncoupling protein 2	97(1,1,3,7)	Details
NK2	94(1,1,2,9)	Details
demethylase	93(1,1,1,13)	Details
tissue transglutaminase	93(1,1,1,13)	Details
bradykinin	93(1,1,1,13)	Details
gp91phox	92(1,1,2,7)	Details
glial fibrillary acidic protein	89(1,1,1,9)	Details
thrombin activatable fibrinolysis inhibitor	89(1,1,1,9)	Details
plasminogen activator inhibitor	87(1,1,1,7)	Details
MP2	86(1,1,1,6)	Details
NF kappa B	85(1,1,1,5)	Details
AT2	84(1,1,1,4)	Details
fibroblast growth factor 9	83(1,1,1,3)	Details
protein p8	83(1,1,1,3)	Details
phospholipase A2	82(1,1,1,2)	Details
ADAM metallopeptidase with thrombospondin type 1 motif (protein family or complex)	82(1,1,1,2)	Details
MR 1	81(1,1,1,1)	Details
tumor necrosis factor receptor (protein family or complex)	81(1,1,1,1)	Details
bile salt export pump	81(1,1,1,1)	Details
whistle	81(1,1,1,1)	Details
histamine H3 receptor	81(1,1,1,1)	Details
alpha Tocopherol transfer protein	81(1,1,1,1)	Details
alanine aminotransferase	430(0,4,14,260)	Details
aspartate aminotransferase	328(0,4,8,188)	Details
catalase	270(0,3,13,130)	Details
interleukin 22	108(0,3,3,18)	Details
TIMP	218(0,2,4,148)	Details
interleukin 1beta	103(0,2,3,38)	Details
PPAR alpha	90(0,2,4,20)	Details
PDGFR	89(0,2,2,29)	Details
CD14	68(0,2,2,8)	Details
Rho kinase	67(0,2,2,7)	Details
tumor necrosis factor alpha	125(0,1,3,85)	Details
connective tissue growth factor	119(0,1,7,59)	Details
CCL4	92(0,1,6,37)	Details
caspase 3	86(0,1,4,41)	Details
Epimorphin	83(0,1,5,33)	Details
peroxisome proliferator activated receptor gamma	75(0,1,2,40)	Details
metalloproteinase	65(0,1,1,35)	Details
proliferating cell nuclear antigen	63(0,1,2,28)	Details
cyclooxygenase 2	55(0,1,1,25)	Details
PPAR delta	54(0,1,3,14)	Details
bcl 2	53(0,1,2,18)	Details
p38	52(0,1,1,22)	Details
basic fibroblast growth factor	51(0,1,2,16)	Details
interferon (protein family or complex)	49(0,1,2,14)	Details
5 lipoxygenase	48(0,1,2,13)	Details
Cl 2	46(0,1,2,11)	Details
Fas Ligand	46(0,1,3,6)	Details
plasmin	46(0,1,1,16)	Details
Yb 1	44(0,1,2,9)	Details
AT1	43(0,1,1,13)	Details
caspase (protein family or complex)	42(0,1,1,12)	Details
PARP 1	42(0,1,2,7)	Details
sPLA2	42(0,1,1,12)	Details
ADAMTS 13	41(0,1,1,11)	Details
STAT5	39(0,1,1,9)	Details
ALDH2	38(0,1,1,8)	Details
KGFR	37(0,1,1,7)	Details
insulin like growth factor binding protein 1	37(0,1,1,7)	Details
CD90	37(0,1,1,7)	Details
choline kinase alpha	36(0,1,1,6)	Details
CCl 3	36(0,1,1,6)	Details
EZH2	35(0,1,1,5)	Details
oncostatin M receptor	35(0,1,1,5)	Details
Alpha fetoprotein regulator	34(0,1,1,4)	Details
RAGE	33(0,1,1,3)	Details
pregnane X receptor	33(0,1,1,3)	Details
5 HT 2	33(0,1,1,3)	Details
IGFBP	31(0,1,1,1)	Details
smooth muscle actin	111(0,0,1,106)	Details
lactate dehydrogenase (protein family or complex)	60(0,0,3,45)	Details
glutathione S transferase	59(0,0,2,49)	Details
gamma glutamyl transferase	46(0,0,1,41)	Details
laminin (protein family or complex)	44(0,0,3,29)	Details
VEGF	41(0,0,1,36)	Details
leptin	40(0,0,2,30)	Details
plasminogen	35(0,0,1,30)	Details
CAPE	34(0,0,3,19)	Details
transferase	34(0,0,1,29)	Details
transforming growth factor beta 1	33(0,0,1,28)	Details
Smad (protein family or complex)	33(0,0,2,23)	Details
S1P	31(0,0,2,21)	Details
Hepatoma derived growth factor	29(0,0,1,24)	Details
chemokine	28(0,0,1,23)	Details
Toll like receptor 4	27(0,0,3,12)	Details
alpha fetoprotein	26(0,0,1,21)	Details
interferon gamma	26(0,0,1,21)	Details
angiotensin II	25(0,0,1,20)	Details
osteopontin	25(0,0,0,25)	Details
granulocyte colony stimulating factor	24(0,0,3,9)	Details
CD8	23(0,0,0,23)	Details
glutathione reductase	23(0,0,0,23)	Details
transferrin	22(0,0,3,7)	Details
cytochrome c	22(0,0,1,17)	Details
gelatinase	21(0,0,0,21)	Details
Fas receptor	21(0,0,3,6)	Details
HSP72	20(0,0,1,15)	Details
Ghrelin	19(0,0,1,14)	Details
superoxide dismutase 1	19(0,0,2,9)	Details
metallothionein (protein family or complex)	19(0,0,1,14)	Details
prothrombin	19(0,0,0,19)	Details
TIMP 2	18(0,0,0,18)	Details
Telomerase (protein family or complex)	18(0,0,1,13)	Details
cytoglobin	18(0,0,1,13)	Details
C met	18(0,0,0,18)	Details
angiopoietin 1	17(0,0,1,12)	Details
ERK1	17(0,0,0,17)	Details
Lactoferrin	17(0,0,2,7)	Details
CXCL10	17(0,0,2,7)	Details
Acetylcholinesterase	17(0,0,1,12)	Details
matrix metalloproteinase 13	16(0,0,0,16)	Details
CK19	16(0,0,0,16)	Details
necl 5	16(0,0,1,11)	Details
spermidine spermine N1 acetyltransferase	16(0,0,1,11)	Details
desmin	16(0,0,0,16)	Details
cytokeratin 8	16(0,0,2,6)	Details
xanthine oxidase	16(0,0,1,11)	Details
CD4	16(0,0,0,16)	Details
FGF2	16(0,0,1,11)	Details
ST2	15(0,0,1,10)	Details
sialyltransferase	14(0,0,1,9)	Details
survivin	14(0,0,1,9)	Details
hTERT	14(0,0,1,9)	Details
angiotensin converting enzyme 2	14(0,0,0,14)	Details
p65	14(0,0,1,9)	Details
paraoxonase 1	14(0,0,0,14)	Details
CD34	14(0,0,1,9)	Details
STAT1	14(0,0,1,9)	Details
Galectin 3	13(0,0,0,13)	Details
microRNA	13(0,0,0,13)	Details
CC1	13(0,0,1,8)	Details
Urokinase type plasminogen activator	13(0,0,0,13)	Details
alpha melanocyte stimulating hormone	12(0,0,1,7)	Details
CYP1A2	12(0,0,0,12)	Details
follicle stimulating hormone (protein family or complex)	12(0,0,2,2)	Details
SALP	12(0,0,1,7)	Details

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