6G33

Dual specificity protein kinase clk1

RCSB Kinase

Target Species: Human
Kinase Family: CLK
Kinase Group: CMGC
Mutation: No

Resolution: 2.05
Release Year: 2018

Kinase Alias: CLK/STY, CLK1, STY, CLK
Downstream Molecules: SPF45, SR protein, PTP-1B
Associated Diseases: Alzheimer's Disease

Ligand ID: 5ID

RCSB Ligand

Ligand Type: Type I Inhibitor
Binding Pocket: ATP domain
Key Interaction Residues: Leu243, Leu244, Gly245
Binding Data: ~
Ligand SMILES: N1=C2[C@H](C=C1)C(=NC=N2)N
Reference: 10.1002/anie.201801666