5N4V

Serine/threonine-protein kinase PIM1

RCSB Kinase

Target Species: Human
Kinase Family: PIM
Kinase Group: CAMK
Mutation: No

Resolution: 1.85
Release Year: 2017

Kinase Alias: PIM, PIM1
Downstream Molecules: MAP3K5, MYC
Associated Diseases: Acute Myeloid Leukemia, Breast Cancer

Ligand ID: 8MW

RCSB Ligand

Ligand Type: Type I Inhibitor
Binding Pocket: ATP domain
Key Interaction Residues: Glu121, Arg122, Pro123
Binding Data: ~
Ligand SMILES: c1(nc2sc(C(=O)O)c(C)c2c(C)n1)C1CC1
Reference: ---