5FP6

Cyclin dependent kinase 2 CDK2

RCSB Kinase

Target Species: Human
Kinase Family: CDK
Kinase Group: CMGC
Mutation: No

Resolution: 1.85
Release Year: 2015

Kinase Alias: p33(CDK2, p33(CDK2), CDK2, p33CDK2, P34cdk2
Downstream Molecules: SAMHD1, E2F-1, retinoblastoma protein
Associated Diseases: Colon Cancer, Prostate Cancer

Ligand ID: MFZ

RCSB Ligand

Ligand Type: Type I Inhibitor
Binding Pocket: ATP domain
Key Interaction Residues: Glu81, Ser82, Leu83
Binding Data: ~
Ligand SMILES: OCC#Cc1c[nH]c2c(Cl)ccc(Cl)c12.OCC#Cc1c[nH]c2c(Cl)ccc(Cl)c12
Reference: 10.1073/pnas.1518946112