5DW2

Bromodomain-containing protein 4

RCSB Kinase

Target Species: Human
Kinase Family: BRD
Kinase Group: Atypical
Mutation: No

Resolution: 1.12
Release Year: 2015

Kinase Alias: BRD4, MCAP, CAP, HUNKI
Downstream Molecules: NF-κB, c-MYC
Associated Diseases: Cancer

Ligand ID: 5GD

RCSB Ligand

Ligand Type: Competitive Inhibitor
Binding Pocket: BRD domain
Key Interaction Residues: Asn156, Ile162, Tyr155
Binding Data: Kd=1.44uM
Ligand SMILES: c1(cc(cc(c1C(=O)N)OC)OC)N
Reference: 10.1016/j.bbrc.2016.06.021