5CI7

Serine/threonine-protein kinase ULK1

RCSB Kinase

Target Species: Human
Kinase Family: ULK
Kinase Group: Other
Mutation: No

Resolution: 1.74
Release Year: 2015

Kinase Alias: FLJ38455, Unc51.1, ULK1, UNC51, ATG1
Downstream Molecules: AMPK
Associated Diseases: Breast Cancer

Ligand ID: 51W

RCSB Ligand

Ligand Type: Type I Inhibitor
Binding Pocket: ATP domain
Key Interaction Residues: Asn96, Cys95, Tyr94
Binding Data: IC50=120nM
Ligand SMILES: N(c1cccc(c1)NC(=O)N1CCCC1)c1ncc(c(NCCCN)n1)I
Reference: 10.1016/j.bmc.2015.07.034