4L3J

Ribosomal protein S6 kinase beta-1 PRS6KB1

RCSB Kinase

Target Species: Human
Kinase Family: RSK
Kinase Group: AGC
Mutation: No

Resolution: 2.1
Release Year: 2013

Kinase Alias: p70(S6K)-alpha, p70s6k, S6K, STK14A, S6K1, p70S6K, RPS6KB1, PS6K, p70-alpha, p70-S6K
Downstream Molecules: RPS6
Associated Diseases: Prostate Cancer, Lung Cancer

Ligand ID: 5FI

RCSB Ligand

Ligand Type: Type I Inhibitor
Binding Pocket: ATP domain
Key Interaction Residues: Glu150, Tyr151, Leu152
Binding Data: ~
Ligand SMILES: c1(c(cncn1)CC)N1CCN(Cc2nc3ccc(C(F)(F)F)cc3[nH]2)CC1
Reference: 10.1042/BJ20121863