3COH

Serine/threonine-Transferase 6 STK6

RCSB Kinase

Target Species: Human
Kinase Family: Aur
Kinase Group: Other
Mutation: No

Resolution: 2.7
Release Year: 2009

Kinase Alias: MGC34538, BTAK, STK7, STK15, AURORA2, AURA, AIK, AurA, STK6, ARK1, AURKA
Downstream Molecules: BORA, BRCA1, CDC25B
Associated Diseases: Pancreatic Carcinoma

Ligand ID: 83H

RCSB Ligand

Ligand Type: Type I Inhibitor
Binding Pocket: ATP domain
Key Interaction Residues: Ala213, Tyr212, Glu211
Binding Data: IC50=4nM
Ligand SMILES: c12c(cc3N(C(=O)C(C)(C)c3c1)CC)c1CCCc3c(c1[nH]2)[nH]nc3C
Reference: 10.1021/jm800052b