2Z2W

Wee1-like protein kinase WEE1

RCSB Kinase

Target Species: Human
Kinase Family: WEE
Kinase Group: Other
Mutation: No

Resolution: 2.22
Release Year: 2007

Kinase Alias: FLJ16446, Wee1, WEE1, DKFZp686I18166, WEE1hu
Downstream Molecules: CDK1
Associated Diseases: Ovarian Cancer, Lung Cancer

Ligand ID: 770

RCSB Ligand

Ligand Type: Type I Inhibitor
Binding Pocket: ATP domain
Key Interaction Residues: Glu377, Tyr378, Cys379
Binding Data: ~
Ligand SMILES: Clc1ccccc1[C@@H]1[C@H]2C(=O)NC(=O)[C@H]2[C@H]2[C@H](C1)N[C@H]1[C@H]2C[C@@H](CC1)/N=C\O
Reference: ---