2CDZ

Serine/threonine-protein kinase pak 4

RCSB Kinase

Target Species: Human
Kinase Family: STE20
Kinase Group: STE
Mutation: No

Resolution: 2.3
Release Year: 2006

Kinase Alias: PAK4
Downstream Molecules: MAP2K6, MAP2K4
Associated Diseases: Pancreatic Cancer, Hepatocellular Carcinoma

Ligand ID: 23D

RCSB Ligand

Ligand Type: Type I Inhibitor
Binding Pocket: ATP domain
Key Interaction Residues: Glu396, Ser397, Leu398
Binding Data: ~
Ligand SMILES: c1c(Cl)cccc1NC1=[N]=[C](=Nc2c1ncn2CC)N[C@@H]1CCCC[C@H]1N
Reference: 10.1016/j.str.2007.01.001