1E98

Thymidylate kinase

RCSB Kinase

Target Species: Human
Kinase Family: TMD
Kinase Group: Other
Mutation: No

Resolution: 1.9
Release Year: 2001

Kinase Alias: CDC8, TMPK, TYMK
Downstream Molecules: DUDP, DUMP, DTDP, DTMP
Associated Diseases: Smallpox, Cancer

Ligand ID: ATM

RCSB Ligand

Ligand Type: Competitive Inhibitor
Binding Pocket: ATP domain
Key Interaction Residues: Thr21, Ser20, Arg16
Binding Data: ~
Ligand SMILES: P(=O)(O)(O)OC[C@H]1O[C@H](C[C@@H]1N[N]#N)N1C(=O)NC(=C(C)C1)O
Reference: 10.1006/jmbi.2000.4175